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Comparison

SAMSN Antibody

Item no. PRS-7079-0.02mg
Manufacturer ProSci
Amount 0.02 mg
Quantity options 0.02 mg 0.1 mg
Category
Type Antibody Polyclonal
Format Liquid
Applications WB, IF, ICC, ELISA
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Conjugate/Tag Unconjugated
Citations Uchida T, Nakao A, Nakano N, et al. Identification of Nash1, a novel protein containing a nuclear localization signal, a sterile alpha motif, and an SH3 domain preferentially expressed in mast cells. Biochem. Biophys. Res. Commun. 2001; 288:137-41.
Claudio JO, Zhu YX, Benn SJ, et al. HACS1 encodes a novel SH3-SAM adaptor protein differentially expressed in normal and malignant hematopoietic cells. Oncogene 2001; 20:5373-7.
Zhu YX, Benn S, Li ZH, et al. The SH3-SAM adaptor HACS1 is up-regulated in B cell activation signaling cascades. J. Exp. Med. 2004; 200:737-47.
Wang D, Stewart AK, Zhuang L, et al. Enhanced adaptive immunity in mice lacking the immunoinhibitory adaptor Hacs1. FASEB J. 2010; 24:947-56.
NCBI SAMSN1
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias SAMSN Antibody: SLy2,HACS1,NASH1,SASH2,SH3D6B,SAM domain-containing protein SAMSN-1,Hematopoietic adaptor containing SH3 and SAM domains 1
Shipping Condition Cool pack
Available
Manufacturer - Type
Primary Antibodies
Shipping Temperature
Blue Ice
Storage Conditions
SAMSN antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight
41 kDa
Manufacturer - Research Area
Immunology
Background
SAMSN Antibody: SAMSN (HACS1) is a member of a novel gene family of putative adaptors and scaffold proteins containing SH3 and SAM (sterile alpha motif) domains. It encodes a 441 amino acid protein that is differentially expressed in hematopoietic cells and malignancies including myeloid leukemia, lymphoma, and myeloma. SAMSN has restricted expression in human tissues. It has been shown to be up-regulated by B cell activation signals and is a participant in B cell activation and differentiation. SAMSN is an immunoinhibitory adaptor that might be a useful target for immune suppression therapy.
By Type
Immunology
Badges
Trial Size
Modifications
None
Protein Gi #
48762709
Purification
SAMSN Antibody is affinity chromatography purified via peptide column.
Positive Control 1
PRS-1201-0.1mg
Positive Control 2
PRS-17-001-1pack
Concentration
1 mg/mL
Buffer
SAMSN Antibody is supplied in PBS containing 0.02% sodium azide.
Application Note
SAMSN antibody can be used for detection of SAMSN by Western blot at 1 - 2 μ g/mL.
Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Homology
Predicted species reactivity based on immunogen sequence: Mouse: (94%)
Manufacturer - Specificity
At least two isoforms of SAMSN are known to exist.
Immunogen
Rabbit polyclonal SAMSN antibody was raised against an 18 amino acid peptide near the carboxy terminus of human SAMSN.

The immunogen is located within the last 50 amino acids of SAMSN.
Clonality
Polyclonal
NCBI Official Name
SAM domain, SH3 domain and nuclear localization signals 1
NCBI Organism
homo sapiens
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note
Optimal dilutions for each application to be determined by the researcher.
SAMSN Antibody
SAMSN Antibody
SAMSN Antibody
SAMSN Antibody
SAMSN Antibody
SAMSN Antibody
SAMSN Antibody
SAMSN Antibody
SAMSN Antibody

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.02 mg
Available: In stock
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