TNFSF4 Antibody

blue ice or room temperature

20 kDa

TNFSF4 Antibody: The tumor necrosis factor superfamily member TNFSF4 is a type II membrane bound, non-covalently linked homotrimeric protein. It is expressed on antigen presenting cells, such as dendritic cells and activated B-cells, and also on other cells such as vascular endothelial cells, mast cells, and natural killer cells. TNFSF4 signals specifically through the TNFRSF4 receptor, is expressed predominantly on CD4+T cells but also on certain activated CD8+T cells. TNFRSF4/TNFSF4 functions as a costimulatory signal, which is required for a productive interaction between antigen presenting cells and their target T-cells. It enhances cell proliferation and survival, and increases expression of RANTES, IL-2, IL-3, and IFNγ . TNFRSF4/TNFSF4 signaling plays an important role in immunotolerance.

TNFSF4 Antibody is affinity chromatography purified via peptide column.

PRS-10-901-4um

TNFSF4 Antibody is supplied in PBS containing 0.02% sodium azide.

Rabbit polyclonal TNFSF4 antibody was raised against a 14 amino acid peptide near the carboxy terminus of human TNFSF4.

The immunogen is located within the last 50 amino acids of TNFSF4.

tumor necrosis factor (ligand) superfamily, member 4

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.