ERRF Antibody

blue ice or room temperature

Predicted: 19 kDa
Observed: 15 kDa

ERRF Antibody: The estrogen receptor-related factor (ERRF) is a recently identified protein whose expression is upregulated in multiple cell lines and primary breast cancer tumors. Increased ERRF expression was significantly associated with ER or progesterone receptor (PR) positivity even in HER2-negative tumors. This higher ERRF expression correlated with better disease-free survival and overall survival. In two ER-positive breast cancer cell lines, knockdown of ERRF suppressed cell growth in vitro and tumorigenesis in xenograft models, suggesting that ERRF plays a role in estrogen-ER-mediated breast cancer cell growth and may thus be a potential therapeutic target.

ERRF Antibody is affinity chromatography purified via peptide column.

PRS-1288-0.1mg

1 mg/ml

ERRF antibody was raised against a 15 amino acid peptide near the carboxy terminus of human ERRF .

The immunogen is located within the last 50 amino acids of ERRF.

chromosome 1 open reading frame 64

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.