TIAF Antibody

Blue Ice

Predicted: 13 kDa
Observed: 14 kDa

TIAF Antibody: TIAF-1 (TGFB1-induced anti-apoptotic factor 1), also known as MYO18A, is a TGFB1-induced anti-apoptotic factor that functions to inhibit the cytotoxic effects of TNF-alpha, TRADD and FADD. It localizes to the nucleus and significantly up-regulated in activated helper T lymphocytes (TH2) in chronic kidney and liver allograft rejection. Suppression of TIAF1 expression by siRNA prevents UV irradiation-mediated p53 phosphorylation and nuclear translocation. TIAF1 is essential in the p53- and WOX1-mediated cell death and shows an aggregation-dependent control of tumor progression and metastasis, and regulation of cell death.

Trial Size

17978509

PRS-1204-0.1mg

1 mg/mL

TIAF Antibody can be used for detection of TIAF by Western blot at 1 μ g/mL.
Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested.

TIAF antibody was raised against a 16 amino acid peptide near the amino terminus of human TIAF .

The immunogen is located within the first 50 amino acids of TIAF.

TGFB1-induced anti-apoptotic factor 1

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.