IL-17RA Antibody

Primary Antibodies

IL-17RA antibody can be stored at 4˚ C up to one year. Antibodies should not be exposed to prolonged high temperatures.

Other IL-17RA antibodies show similar size band

IL-17RA Antibody: Interleukin 17A (IL-17A) is a proinflammatory cytokine secreted by activated T-lymphocytes (1). It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. IL-17RA is a ubiquitous type I membrane glycoprotein that binds with low affinity to IL-17A and IL-17F (1, 2). IL-17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis (3, 4). Defects in IL-17RA are the cause of familial candidiasis type 5 (CANDF5) which is a rare disorder with altered immune responses and impaired clearance of fungal infections (5).

Trial Size

23238208

PRS-1409-0.1mg

1 mg/mL

WB: 1-4 μ g/mL; IHC-P/IF: 10-20 μ g/mL.

Antibody validated: Western Blot in human and mouse samples; Immunofluorescence in human and mouse samples. All other applications and species not yet tested.

IL-17RA antibody was raised against an 18 amino acid peptide near the amino terminus of human IL-17RA.

The immunogen is located within amino acids 150 - 200 of IL-17RA.

interleukin 17 receptor A

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.