Manufacturer |
ProSci
|
Category |
|
Type |
Antibody Polyclonal |
Specific against |
Human, Mouse, Rat |
Format |
Liquid |
Applications |
WB |
Amount |
0.1 mg |
Host |
Rabbit |
Item no. |
PRS-79-945-0.1mg |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Available |
|
Shipping |
blue ice or RT |
By Research Area |
Phospho-Specific |
Immunogen |
FGFR4 (phospho Tyr642) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 642 (I-D-Y (p)-Y-K) derived from Human FGFR4 . |
Applications |
Western Blot: 1:500~1:1000 |
Specificity |
The antibody detects endogenous levels of FGFR4 only when phosphorylated at tyrosine 642. |
Predicted Molecular Weight |
90 kDa |
Purification |
Antibodies were purified by affinity-chromatography using epitope-specific peptide. |
Clonality |
Polyclonal |
Isotype |
IgG |
Conjugate |
Unconjugated |
Buffer |
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Concentration |
1 mg/mL |
Storage Conditions |
Store antibody at -20˚ C for up to one year. |
Disclaimer |
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only. |
Modifications |
Phospho-Specific |
Ncbi Official Symbol |
FGFR4 |
Accession # |
NP_002002.3 |
Protein Gi # |
47524173 |
Ncbi Gene Id # |
2264 |
Ncbi Official Symbol |
FGFR4 |
Ncbi Official Full Name |
fibroblast growth factor receptor 4 |
Ncbi Organism |
Homo sapiens |
Swissprot # |
P22455 |
Background |
Receptor for acidic fibroblast growth factor. Does not bind to basic fibroblast growth factor. Binds FGF19. |
Background References 1 |
Partanen J.M., EMBO J. 10:1347-1354(1991) [PubMed: 1709094]. |
Background References 2 |
Ron D., J. Biol. Chem. 268:5388-5394(1993) [PubMed: 7680645]. |
Background References 3 |
Takaishi S., Biochem. Biophys. Res. Commun. 267:658-662(2000) [PubMed: 10631118]. |
1st Image Caption |
Western blot analysis of extracts from JK cells (Lane 2), using FGFR4 (Phospho-Tyr642) Antibody. The lane on the left is treated with antigen-specific peptide. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.