MAP1LC3 Antibody

Blue Ice

Predicted: 13 kDa
Observed: 18 kDa

Microtubule-associated proteins (MAPs) regulate microtubule stability and play critical roles in neuronal development and plasticity (1). MAP1LC3 is a subfamily of three related proteins belonging to the MAP1 LC3 family and it includes MAP1LC3A, MAP1LC3B, and MAP1LC3C (2). MAP1LC3 is the mammalian homolog of yeast ATG8 and is essential for autophagy and associated with the autophagosome membranes after processing (3). The three isoforms exhibit distinct expression patterns and both MAP1LC3A and MAP1LC3B but not MAP1LC3B, are post-translationally modified, suggesting the three isoforms may have different physiological functions (4).

Trial Size

14210522

PRS-1303-0.1mg

MAP1LC3 antibody is supplied in PBS containing 0.02% sodium azide.

Predicted species reactivity based on immunogen sequence: Bovine: (100%)

MAP1LC3 antibody was raised against a 12 amino acid peptide near the center of human MAP1LC3A.

The immunogen is located within amino acids 20 - 70 of MAP1LC3.

microtubule-associated protein 1 light chain 3 alpha

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.