Comparison

SARS-CoV-2 (COVID-19) NSP16 Antibody

Item no. PRS-9271-0.1mg
Manufacturer ProSci
Amount 0.1 mg
Quantity options 0.02 mg 0.1 mg
Category
Type Antibody Polyclonal
Format Liquid
Applications WB, IHC, ELISA
Specific against Virus
Host Rabbit
Isotype IgG
Conjugate/Tag Unconjugated
Citations Gorbalenya. bioRxiv: 2020.
Hui et al. Int J Infect Dis. 2020;91:264-266.
NCBI NSP16
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias 2'-O-methyltransferase,nsp16,Non-structure protein 16
Shipping Condition Cool pack
Available
Manufacturer - Type
Primary Antibodies
Shipping Temperature
Blue Ice
Storage Conditions
SARS-CoV-2 (COVID-19) NSP16 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Manufacturer - Research Area
Infectious Disease, COVID-19
Background
Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1). The disease is the cause of the 2019–20 coronavirus outbreak (2). The structure of 2019-nCoV consists of the following: a spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA.
Methyltransferase mediates mRNA cap 2'-O-ribose methylation to the 5'-cap structure of viral mRNAs. N7-methyl guanosine cap is a prerequisite for binding of nsp16. Therefore plays an essential role in viral mRNAs cap methylation which is essential to evade immune system.
By Type
Infectious Disease, COVID-19
Badges
Trial Size, New
Protein Gi #
1819735431
Purification
SARS-CoV-2 (COVID-19) NSP16 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL
Buffer
SARS-CoV-2 (COVID-19) NSP16 antibody is supplied in PBS containing 0.02% sodium azide.
Application Note
IHC: 0.5 μ g/mL; WB: 0.5 μ g/mL
Antibody validated: Immunohistochemistry in human samples. SARS-CoV-2 (COVID-19) NSP16 antibody can detect 2 ng of free peptide at 1 μ g/mL in ELISA. It can detect SARS-CoV-2 NSP16 recombinant protein by ELISA and WB. All other applications and species not yet tested.
Homology
Predicted reactivity based on immunogen sequence: SARS-CoV NSP16 protein: (88%).
Immunogen
Anti-SARS-CoV-2 (COVID-19) NSP16 antibody (9271) was raised against a peptide corresponding to 16 amino acids near the central domain of SARS-CoV-2 (COVID-19) NSP16 protein.

The immunogen is located within 120-170 amino acids of the SARS-CoV-2 (COVID-19) NSP16 protein.
Clonality
Polyclonal
NCBI Official Name
ORF1a polyprotein; ORF1ab polyprotein
NCBI Organism
Severe acute respiratory syndrome coronavirus 2
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note
Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 0.1 mg
Available: In stock
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