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SARS-CoV-2 (COVID-19) ORF8 Antibody

SARS-CoV-2 (COVID-19) ORF8 Antibody

Item no.	PRS-9289-0.1mg
Manufacturer	ProSci
Amount	0.1 mg
Quantity options	0.02 mg 0.1 mg
Category	Infectious Diseases Viral Infections Coronavirus (COVID-19) Antibodies Western Blot ELISA Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, ELISA
Specific against	Virus
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Citations	Gorbalenya. bioRxiv: 2020. Hui et al. Int J Infect Dis. 2020;91:264-266. Chan et al. Lancet. 2020; 395:514-523.
NCBI	ORF8
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ORF8 protein,ns8,ORF8,Non-structural protein 8
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	SARS-CoV-2 (COVID-19) ORF8 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight	14kD
Manufacturer - Research Area	Infectious Disease, COVID-19
Background	Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1). The disease is the cause of the 2019–20 coronavirus outbreak (2). SARS-CoV-2 virus proteins include structural proteins, non-structural proteins and accessory factors. The structure of SARS-CoV-2 consists of the following: a spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. SARS-CoV-2 non-structural protein is ORF1ab that consists of 16 proteins (nsp1-nsp16), while accessory factors include ORF3a, ORF3b, ORF6, ORF7a, ORF7b, ORF8, ORF9b, ORF9c and ORF10. ORF8 may play a role in modulating host immune response (Probable). May play a role in blocking host IL17 cytokine by its interaction with host IL17RA (3).
By Type	Infectious Disease, COVID-19
Badges	Trial Size, New
Protein Gi #	1835921949
Purification	SARS-CoV-2 (COVID-19) ORF8 Antibody is affinity chromatography purified via peptide column.
Concentration	1 mg/mL
Buffer	SARS-CoV-2 (COVID-19) ORF8 antibody is supplied in PBS containing 0.02% sodium azide.
Application Note	WB: 1 μ g/mL Antibody validated: SARS-CoV-2 (COVID-19) ORF8 antibody can detect 2 ng of free peptide at 1 μ g/mL in ELISA. It can detect SARS-CoV-2 ORF8 recombinant protein by WB. All other applications and species not yet tested.
Manufacturer - Specificity	ORF8 Antibody is predicted to not cross-react with other coronavirus family members.
Immunogen	Anti-SARS-CoV-2 (COVID-19) ORF8 antibody (9289) was raised against a peptide corresponding to 13 amino acids near the central domain of SARS-CoV-2 (COVID-19) ORF8 protein. The immunogen is located within 30-80 amino acids of the SARS-CoV-2 (COVID-19) ORF8 protein.
Clonality	Polyclonal
NCBI Official Name	ORF8 protein
NCBI Organism	Severe acute respiratory syndrome coronavirus 2
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg

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Delivery expected until 12/4/2025

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