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Rabbit anti-Human IL-6 mAb (DET)

Rabbit anti-Human IL-6 mAb (DET)

Item no.	RM17630-100ug
Manufacturer	Abclonal
Amount	100 ug
Category	Antibodies Immunoassay Secondary Antibodies CLIA
Type	Antibody Monoclonal
Applications	CLIA
Specific against	other
Isotype	IgG
Purity	Affinity purification
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Available
Manufacturer - Category	Primary antibody(DET)
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free.
Background	Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable). The interaction with the membrane-bound IL6R and IL6ST stimulates ‘‘classic signaling’‘, whereas the binding of IL6 and soluble IL6R to IL6ST stimulates ‘‘trans-signaling’‘. Alternatively, ‘‘cluster signaling’‘ occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells (Probable).
Manufacturer - Cross Reactivity	No cross-reactivity in ELISA and WB with Recombinant human CNTF, IL-2 , IL-3, G-CSF, IL-4 , M-CSF, IL-5 , IL-1A, IL-1B , IL-6RA, IL-6RB, IL-7, IL-8&Recombinant mouse IL-6, IL-2, IL-4, IL-11, IL-12
Immunogen	E. coli-derived human IL-6 protein Pro29-Met212 Accession #Q75MH2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 12/18/2025

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