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Anti-SARS-CoV-2 Spike RBD Antibody, Chimeric mAb, Human IgG1 (AS113) (Omicron Specific) European Partner

Item no. SPD-M415-100ug
Manufacturer ACROBiosystems
Amount 100 ug
Quantity options 100 ug 1 mg
Category
Type Antibody Monoclonal
Format Solid
Specific against Human (Homo sapiens)
Host HEK293
Isotype IgG1
Conjugate/Tag Unconjugated
Purity 95%
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Shipping Condition Room temperature
Available
Manufacturer - Category
Antibody / Recombinant Antibodies
Manufacturer - Conjugate / Tag
Human IgG1 | Human Kappa, Unconjugated
Shipping Temperature
RT
Storage Conditions
-20°C
Manufacturer - Format
Powder
Description
Anti-SARS-CoV-2 Spike RBD Antibody, Human IgG1 (AS113) (Omicron Specific) is a chimeric monoclonal antibody recombinantly expressed from HEK293 cells, which combines the variable region of a mouse monoclonal antibody with human IgG1 constant domain. The mouse monoclonal antibody is produced from a hybridoma resulting from fusion of SP2/0 myeloma and B-lymphocytes obtained from a mouse immunized with omicron Spike RBD. The antibody is specific against the Omicron (B.1.1.529/BA.1) variant of SARS-CoV-2, and has no binding with the spike RBD of the wild type virus and other viral lineages.
Background
It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
Molecule
Spike RBD
Buffer
PBS, pH 7.4
Stability
● -20°C to -70°C for 12 months in lyophilized state;
● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower._x000D_Please avoid repeated freeze-thaw cycles.
Protectant
trehalose

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
available

Delivery expected until 7/31/2025 

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