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PBRM1 Antibody - middle region

PBRM1 Antibody - middle region

Item no.	ARP39332_P050
Manufacturer	AVIVA Systems Biology
Amount	100 ul
Category	Oncology Assisted reproductive technologies Embryo manipulation Antibodies By Cell Type Carcinoma Melanoma Western Blot Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Guinea Pig, Dog (Canine, Canis lupus familiaris), Horse (Equine), Zebrafish (Danio rerio), Cow (Bos taurus)
Host	Rabbit
Sequence	SAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALW
Citations	smarce1 mutants have a defective endocardium and an increased expression of cardiac transcription factors in zebrafish. Sci Rep. 8, 15369 (2018). 30337622 Xia,W., (2008) Cancer Res. 68 (6), 1667-1674
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	PB1,BAF180
Similar products	PBRM1
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Polyclonal Antibodies/Transcription Factor, Root Catalog/Products/Polyclonal Antibodies/Signal Proteins, Root Catalog/Research Areas/Chromatin & Nuclear Signaling, Root Catalog/Research Areas/Disease Related, Root Catalog/Research Areas/DNA\/RNA\/Protein Interactions, Root Catalog/Research Areas/Transcription Factors, Root Catalog/Products/Polyclonal Antibodies/Trial Size Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies, Root Catalog/Products/Aviva Rabbit Polyclonal, Root Catalog/Research Areas/Cancer/Cancer Transcription Factor
Shipping Temperature	Wet Ice
Molecular Weight	181kDa
Species Tested	Human
Gene symbol	PBRM1
Gene Fullname	Polybromo 1
Protein size	1582
Product format	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and storage	For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Partner proteins	SUMO2; CDC20; UBC; EED; HECW2; ZNF512B; WHSC1; NOTCH1; MAML1; TCHHL1; GTF3C5; APP; CALML5; SIRT7; HIST3H3; SMARCD1; SMARCC2; SMARCAD1; SUMO1; SMARCC1; SMARCB1; SMARCA4; ACTL6A; SMARCE1; CHD7; Bcl7b; ARID2; tat; HIST1H4A; HIST1H3A; HIST2H2BE; HIST2H2AC; AR
Description of target	PBRM1 is involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology).
Nucleotide accession_num	NM_018313
Protein accession_num	NP_060783
Protein name	Protein polybromo-1
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	The immunogen is a synthetic peptide directed towards the middle region of human PBRM1
Homology	Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 100%
Concentration	0.5 mg/ml
Sample Type Confirmation	PBRM1 is supported by BioGPS gene expression data to be expressed in HepG2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 10/30/2025

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