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Goat Anti-Insulysin / Insulinase Antibody

Goat Anti-Insulysin / Insulinase Antibody

Item no.	OAEB01559
Manufacturer	AVIVA Systems Biology
Amount	100 ug
Category	Neuroscience Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Regulation of Appetite Protein Aggregation, Clearance & Misfolding Antibodies Immunohistochemistry Western Blot Endocrine Regulation of Lipid Metabolism Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, IHC
Specific against	Human (Homo sapiens), Dog (Canine, Canis lupus familiaris)
Host	Caprine
Sequence	C-QQYNFDRDNTE
Citations	* Zhao Z, Xiang Z, Haroutunian V, Buxbaum JD, Stetka B, Pasinetti GM.; Insulin degrading enzyme activity selectively decreases in the hippocampal formation of cases at high risk to develop Alzheimer's disease.; Neurobiol Aging. 2007 Jun;28(6):824-30. Epub 2006 Jun 12.; Pubmed 16769157
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Abeta-degrading protease;insulin protease;insulinase;insulin-degrading enzyme;INSULYSIN.
Similar products	IDE
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Monoclonal Antibodies/Drugs and Drug Metabolism, Root Catalog/Research Areas/Cell Biology, Root Catalog/Research Areas/Signal Transduction, Root Catalog/Research Areas/Stem Cells, Root Catalog/Research Areas/Immunohistochemistry, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	118, 54
Manufacturer - Application Additional Information	Peptide ELISA: antibody detection limit dilution 1:32000. Western Blot: Approx 110-120kDa band observed in lysates of cell line K562 (calculated MW of 118kDa according to NP_004960.1). In transfected HEK293 transiently expressing Insulysin a band of approx. 110kDa is observed. This band is not observed in the non-transfected HEK293. Recommended concentration: 0.1-0.3ug/ml. IHC: In paraffin embedded Human Lung, shows cytoplasm staining of alveolar macrophages. Recommended concentration, 3-6 ug/ml.
Gene symbol	IDE
Gene Fullname	insulin degrading enzyme
Product format	Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20Â°C. Minimize freezing and thawing.
Reconstitution and storage	Aliquot and store at -20C. Minimize freezing and thawing.
Protein accession_num	NP_004960.1
Protein name	Insulin-degrading enzyme
Clonality	Polyclonal
Purification	Ammonium Sulfate Precipitated; Affinity Purified
Immunogen	IDE
Homology	Cow: 90%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 81%; Pig: 90%; Rabbit: 90%; Rat: 81%; Zebrafish: 90%
Concentration	0.5 mg/ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 11/27/2025

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