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Goat Anti-RACGAP1 / MgcRacGAP Antibody

Goat Anti-RACGAP1 / MgcRacGAP Antibody

Item no.	OAEB02427
Manufacturer	AVIVA Systems Biology
Amount	100 ug
Category	Antibodies Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, IHC
Specific against	Human (Homo sapiens), Dog (Canine, Canis lupus familiaris), Cattle (Bovine)
Host	Caprine
Sequence	C-GRQGNFFASPMLK
Citations	* Seguin L, Liot C, Mzali R, Harada R, Siret A, Nepveu A, Bertoglio J.; CUX1 and E2F1 regulate coordinated expression of the mitotic complex genes Ect2, MgcRacGAP, and MKLP1 in S phase.; Mol Cell Biol. 2009 Jan;29(2):570-81.; Pubmed 19015243 * Grewal S, Carver JG, Ridley AJ, Mardon HJ.; Implantation of the human embryo requires Rac1-dependent endometrial stromal cell migration.; Proc Natl Acad Sci U S A. 2008 Oct 21;105(42):16189-94.; Pubmed 18838676 * Toure A, Mzali R, Liot C, Seguin L, Morin L, Crouin C, Chen-Yang I, Tsay YG, Dorseuil O, Gacon G, Bertoglio J.; Phosphoregulation of MgcRacGAP in mitosis involves Aurora B and Cdk1 protein kinases and the PP2A phosphatase.; FEBS Lett. 2008 Apr 9;582(8):1182-8.; Pubmed 18201571 * Zhao WM, Seki A, Fang G.; Cep55, a microtubule-bundling protein, associateswith centralspindlin to control the midbody integrity and cell abscission during cytokinesis.; Mol Biol Cell. 2006 Sep;17(9):3881-96.; Pubmed 16790497 * Nishimura Y, Yonemura S.; Centralspindlin regulates ECT2 and RhoA accumulation at the equatorial cortex during cytokinesis.; J Cell Sci. 2006 Jan 1;119(Pt 1):104-14. Epub 2005 Dec 13.; Pubmed 16352658 * Reibel L, Dorseuil O, Stancou R, Bertoglio J, Gacon G.; A hemopoietic specific gene encoding a small GTP binding protein is overexpressed during T cell activation.; Biochem Biophys Res Commun. 1991 Mar 15;175(2):451-8.; Pubmed 1902092
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CYK4;HsCYK-4;ID-GAP;male germ cell RacGap;MgcRacGAP;protein CYK4 homolog;rac GTPase-activating protein 1.
Similar products	RACGAP1
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Research Areas/Cell Biology, Root Catalog/Research Areas/Developmental Biology, Root Catalog/Research Areas/Signal Transduction, Root Catalog/Research Areas/Stem Cells, Root Catalog/Research Areas/Meiosis\/Mitosis\/Cell Cycle, Root Catalog/Research Areas/Immunohistochemistry, Root Catalog/Research Areas/Cell Differentiation, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	71.0; 63.9; 72.3; 61.9
Manufacturer - Application Additional Information	Peptide ELISA: antibody detection limit dilution 1:32000. Western Blot: Approx 75kDa band observed in lysates of cell line K562 and Jurkat (calculated MW of 71.0kDa according to NP_037409.2). Recommended concentration: 0.3-1ug/ml. Immunohistochemistry: In paraffin embedded Human Testis, shows nuclear staining of many cells. Recommended concentration, 1ug/ml.
Gene symbol	RACGAP1
Gene Fullname	Rac GTPase activating protein 1
Product format	Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20Â°C. Minimize freezing and thawing.
Reconstitution and storage	Aliquot and store at -20C. Minimize freezing and thawing.
Protein accession_num	NP_037409.2
Protein name	Rac GTPase-activating protein 1
Clonality	Polyclonal
Purification	Ammonium Sulfate Precipitated; Affinity Purified
Immunogen	RACGAP1
Homology	Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Pig: 100%; Rabbit: 92%; Zebrafish: 91%
Manufacturer - Specificity	Reported variants represent identical protein: NP_037409.2, NP_001119576.1 and NP_001119575.1.
Concentration	0.5 mg/ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 11/27/2025

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