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NR1H3 antibody - N-terminal region (ARP38669_T100)

NR1H3 antibody - N-terminal region (ARP38669_T100)

Item no.	ARP38669_T100
Manufacturer	AVIVA Systems Biology
Amount	100ul
Category	Neuroscience Neural Lineage Markers Metabolism Cholesterol & Lipid Metabolism Neural Signaling Antibodies Western Blot Primary Antibodies Other Lipid\Cholesterol Metabolism Modulators
Type	Antibody Polyclonal
Format	Lyophilized powder
Applications	WB
Specific against	Human (Homo sapiens), Porcine, Rabbit (Oryctolagus cuniculus), Bovine, Canine, Equine, Goat (Caprine, Capra aegagrus hircus)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	LXRA, LXR-a, RLD-1
Similar products	NR1H3
Available
Gene symbol	NR1H3
Protein name	Oxysterols receptor LXR-alpha
Protein size	447
Molecular weight	50kDa
Product format	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Gene id	10062
Reconstitution and storage	For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Partner proteins	RXRG. RXRB. MDFI. SUV39H1. KDM1A. BARD1. MSTO1. HSP90AA1. PIAS1. APP. NR3C1. MYC. ZXDC. TMEM161A. ING3. NCOA6. NCOR1. KAT2B. EIF3I. NRIP1. NCOA3. SRC. RXRA. FOXO3. ACTN1. SS18L1. LZTR1. EDF1. RARA. NR0B2. SYT1. PPARA. SIRT1. UBC. CEP350.
Description of target	Interaction of NR1H3 with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. NR1H3 are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. NR1H3 Plays an important role in the regulation of cholesterol homeostasis.
Homology	Cow: 85%; Dog: 79%; Goat: 85%; Horse: 79%; Human: 100%; Pig: 77%; Rabbit: 86%
Purification	Protein A purified
Clonality	Polyclonal
Immunogen	The immunogen is a synthetic peptide directed towards the N terminal region of human NR1H3
Drywet	Wet Ice

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ul

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Delivery expected until 9/25/2025

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