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SMAD7 Antibody - N-terminal region

SMAD7 Antibody - N-terminal region

Item no.	ARP32008_P050
Manufacturer	AVIVA Systems Biology
Amount	100 ul
Category	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Aging & Neurological Disorders Neural Development Neural Adhesion Molecules Antibodies Western Blot Primary Antibodies By Organ Colorectal Cancer Neurodegeneration Markers Glial Cell Markers
Type	Antibody Polyclonal
Format	Liquid
Applications	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Rabbit (Oryctolagus cuniculus), Dog (Canine, Canis lupus familiaris), Pig (Porcine, Sus scrofa domesticus), Cow (Bos taurus)
Host	Rabbit
Sequence	EEEGAGGGGGGGELRGEGATDSRAHGAGGGGPGRAGCCLGKAVRGAKGHH
Citations	Higher Anti-Liver Fibrosis Effect of Cordyceps militaris-Fermented Product Cultured with Deep Ocean Water via Inhibiting Proinflammatory Factors and Fibrosis-Related Factors Expressions. Mar Drugs. 15, (2017). 28594374 Komuro,A., et al., (2004) Oncogene 23 (41), 6914-6923
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CRCS3,MADH7,MADH8
Similar products	SMAD7
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Polyclonal Antibodies/Transcription Factor, Root Catalog/Research Areas/Chromatin & Nuclear Signaling, Root Catalog/Research Areas/Phosphorylation, Root Catalog/Research Areas/Transcription Factors, Root Catalog/Products/Polyclonal Antibodies/Trial Size Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies, Root Catalog/Products/Aviva Rabbit Polyclonal
Shipping Temperature	Wet Ice
Molecular Weight	46kDa
Species Tested	Human
Gene symbol	SMAD7
Gene Fullname	SMAD family member 7
Protein size	426
Product format	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and storage	For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Partner proteins	HDAC3; HDAC2; USP11; SMURF2; SMURF1; SKP2; MYC; Melk; HCVgp1; RNF111; KDM2A; SOX13; PIAS1; SOX7; UBE2O; MKL2; ASH1L; PIAS4; CXXC5; ZNF107; ZBTB11; HEYL; TTF2; UBC; TTF1; SOX5; MYOD1; XRCC6; CTNNB1; MAPK14; BAMBI; PPP1R15A; NEDD4L; STAMBP; YAP1; AXIN1; TP5
Description of target	Smad7 acts to functionally inactivate RB and de-repress E2F without blocking the activation of TbetaRI and the nuclear translocation of Smad2/3, allowing TGF-beta1 to exert effects in a cancer cell that is resistant to TGF-beta1-mediated growth inhibition.
Nucleotide accession_num	NM_005904
Protein accession_num	NP_005895
Protein name	Mothers against decapentaplegic homolog 7
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	The immunogen is a synthetic peptide directed towards the N terminal region of human SMAD7
Homology	Cow: 93%; Dog: 93%; Human: 100%; Mouse: 92%; Pig: 93%; Rabbit: 93%; Rat: 85%
Concentration	0.5 mg/ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 1/29/2026

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