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SMAD7 antibody - N-terminal region (ARP32008_P050)

SMAD7 antibody - N-terminal region (ARP32008_P050)

Item no.	ARP32008_P050
Manufacturer	AVIVA Systems Biology
Amount	100ul
Category	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Aging & Neurological Disorders Neural Development Neural Adhesion Molecules Antibodies Western Blot Primary Antibodies By Organ Colorectal Cancer Neurodegeneration Markers Glial Cell Markers
Type	Antibody Polyclonal
Format	Lyophilized powder
Applications	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Porcine, Rabbit (Oryctolagus cuniculus), Bovine, Canine
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CRCS3, MADH7, MADH8
Similar products	SMAD7
Available
Gene symbol	SMAD7
Protein name	Mothers against decapentaplegic homolog 7
Protein size	426
Molecular weight	46kDa
Product format	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Gene id	4092
Reconstitution and storage	For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Partner proteins	HDAC3. HDAC2. USP11. SMURF2. SMURF1. SKP2. MYC. Melk. HCVgp1. RNF111. KDM2A. SOX13. PIAS1. SOX7. UBE2O. MKL2. ASH1L. PIAS4. CXXC5. ZNF107. ZBTB11. HEYL. TTF2. UBC. TTF1. SOX5. MYOD1. XRCC6. CTNNB1. MAPK14. BAMBI. PPP1R15A. NEDD4L. STAMBP. YAP1. AXIN1. TP5
Description of target	Smad7 acts to functionally inactivate RB and de-repress E2F without blocking the activation of TbetaRI and the nuclear translocation of Smad2/3, allowing TGF-beta1 to exert effects in a cancer cell that is resistant to TGF-beta1-mediated growth inhibition.
Homology	Cow: 93%; Dog: 93%; Human: 100%; Mouse: 92%; Pig: 93%; Rabbit: 93%; Rat: 85%
Purification	Affinity Purified
Clonality	Polyclonal
Immunogen	The immunogen is a synthetic peptide directed towards the N terminal region of human SMAD7
Drywet	Wet Ice

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ul

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Delivery expected until 10/9/2025

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