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Goat Anti-MEL18 / PCGF2 Antibody

Goat Anti-MEL18 / PCGF2 Antibody

Item no.	OAEB01334
Manufacturer	AVIVA Systems Biology
Amount	100 ug
Category	Antibodies Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	WB
Specific against	Human (Homo sapiens), Dog (Canine, Canis lupus familiaris), Cattle (Bovine)
Host	Caprine
Purity	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Sequence	C-KMTVNGAPVPPLT
Citations	* Endoh M, Endo TA, Endoh T, Fujimura Y, Ohara O, Toyoda T, Otte AP, Okano M, Brockdorff N, Vidal M, Koseki H.; Polycomb group proteins Ring1A/B are functionally linked to the core transcriptional regulatory circuitry to maintain ES cell identity.; Development. 2008 Apr;135(8):1513-24.; Pubmed 18339675 * Miki J, Fujimura Y, Koseki H, Kamijo T.; Polycomb complexes regulate cellular senescence by repression of ARF in cooperation with E2F3.; Genes Cells. 2007 Dec;12(12):1371-82.; Pubmed 18076574 * Elderkin S, Maertens GN, Endoh M, Mallery DL, Morrice N, Koseki H, Peters G, Brockdorff N, Hiom K.; A phosphorylated form of Mel-18 targets the Ring1B histone H2A ubiquitin ligase to chromatin.; Mol Cell. 2007 Oct 12;28(1):107-20.; Pubmed 17936708 * Xi S, Zhu H, Xu H, Schmidtmann A, Geiman TM, Muegge K.; Lsh controls Hox gene silencing during development.; Proc Natl Acad Sci U S A. 2007 Sep 4;104(36):14366-71.; Pubmed 17726103 * Ishida A, Asano H, Hasegawa M, Koseki H, Ono T, Yoshida MC, Taniguchi M, Kanno M.; Cloning and chromosome mapping of the human Mel-18 gene which encodes a DNA-binding protein with a new 'RING-finger' motif.; Gene. 1993 Jul 30;129(2):249-55.; Pubmed 8325509
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	DNA-binding protein Mel-18;MEL-18;polycomb group RING finger protein 2;ring finger protein 110;RNF110;TPFS;zinc finger protein 144;ZNF144.
Similar products	PCGF2
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Polyclonal Antibodies/RNA Binding Proteins, Root Catalog/Products/Monoclonal Antibodies/Transcription Regulation, Root Catalog/Research Areas/Developmental Biology, Root Catalog/Research Areas/Epigenetics, Root Catalog/Research Areas/Acetylation, Root Catalog/Research Areas/Transcription Factors, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	37, 8
Manufacturer - Application Additional Information	Peptide ELISA: antibody detection limit dilution 1:16000. Western Blot: Approx 40 kDa band observed in Human Lung lysates (calculated MW of 37.8kDa according to NP_009075.1). Recommended for use at 1-2ug/ml.
Gene symbol	PCGF2
Gene Fullname	polycomb group ring finger 2
Product format	Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20Â°C. Minimize freezing and thawing.
Reconstitution and storage	Aliquot and store at -20C. Minimize freezing and thawing.
Protein accession_num	NP_009075.1
Protein name	Polycomb group RING finger protein 2
Clonality	Polyclonal
Purification	Ammonium Sulfate Precipitated; Affinity Purified
Immunogen	PCGF2
Homology	Cow: 100%; Dog: 100%; Human: 100%; Mouse: 90%; Rabbit: 100%; Rat: 90%
Concentration	0.5 mg/ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 11/27/2025

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