« Back
Home /
Anti-ROCKII Antibody (Phospho-Thr 396) (OAAI00345)

Anti-ROCKII Antibody (Phospho-Thr 396) (OAAI00345)

Item no.	OAAI00345
Manufacturer	AVIVA Systems Biology
Amount	100 ug
Category	Oncology Antibodies By Cell Type Carcinoma Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Bovine, Canine, Gallus
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ROCK-II
Similar products	ROCK-II
Available
Gene symbol	ROCK2
Molecular weight	165 kDa
Product format	Liquid. Sterile Tris-buffered saline (pH 7.2) containing antibody stabilizer
Gene id	9475
Reconstitution and storage	The antibodies are stable for 12 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C to 8C for three months without detectable loss of activity. Avoid repeated freezing thawing cycles.
Description of target	Rho A-dependent kinase (ROCKII), or ROK-alpha, is identified a serine/threonine kinase, a downstream effector of the small GTPase Rho, mediating effects of Rho on the actin cytoskeleton, formation of actin stress fibers and focal adhesions, ROCKII alters cardiac myofilament response to Ca2+ by mechanisms involving phosphorylation of thin filament proteins. ROCK-II induces a depression in maximum ATPase Rate and tension, which is associated with phosphorylation of troponin T (TnT), troponin I (TnI), and myosin-binding protein C (C-protein). The phosphorylation of Rho-kinase at Thr 249, Thr 396 plays important role in G-protein signaling.
Purification	Purified by Site-specific Epitope Affinity Purification
Clonality	Polyclonal
Immunogen	A synthetic peptide corresponding to the epitope -VETFP- with a single phosphorylation site Thr396 of Human RockII protein. This sequence is identical among Human, Mouse, Rat, chicken, dog and bovine.
Drywet	Wet Ice

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

OAAI00345-datasheet.pdf

Request safety datasheet

Simple Order Order Subscription

Amount: 100 ug

available

Delivery expected until 9/25/2025

Compare

Add to wishlist

Get an offer

Request delivery time