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Goat Anti-ENPP1 / PC1 Antibody

Goat Anti-ENPP1 / PC1 Antibody

Item no.	OAEB02445
Manufacturer	AVIVA Systems Biology
Amount	100 ug
Category	Neuroscience Neuroinflammation Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Regulation of Appetite Aging & Neurological Disorders Antibodies Immunohistochemistry Western Blot ELISA Cardiovascular Research Thrombosis & Hemostasis Primary Antibodies Immunostaining
Type	Antibody Polyclonal
Applications	WB, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Caprine
Sequence	C-KTHLPTFSQED
Citations	de la Croix Ndong, J. et al. Asfotase-a improves bone growth, mineralization and strength in mouse models of neurofibromatosis type-1. Nat. Med. 20, 904-10 (2014). 24997609 * Orriss IR, Utting JC, Brandao-Burch A, Colston K, Grubb BR, Burnstock G, Arnett TR.; Extracellular nucleotides block bone mineralization in vitro: evidence for dual inhibitory mechanisms involving both P2Y2 receptors and pyrophosphate.; Endocrinology. 2007 Sep;148(9):4208-16.; Pubmed 17569759 * Meyre D, Bouatia-Naji N, Tounian A, Samson C, Lecoeur C, Vatin V, Ghoussaini M, Wachter C, Hercberg S, Charpentier G, Patsch W, Pattou F, Charles MA, Tounian P, Clement K, Jouret B, Weill J, Maddux BA, Goldfine ID, Walley A, Boutin P, Dina C, Froguel P.; Variants of ENPP1 are associated with childhood and adult obesity and increase the risk of glucose intolerance and type 2 diabetes.; Nat Genet. 2005 Aug;37(8):863-7. Epub 2005 Jul 17.; Pubmed 16025115
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	alkaline phosphodiesterase 1;ARHR2;COLED;ectonucleotide pyrophosphatase/phosphodiesterase family member 1;E-NPP 1;Ly-41 antigen;M6S1;membrane component,chromosome 6,surface marker 1;NPP1;NPPS;PC-1;PCA1;PDNP1;phosphodiesterase I/nucleotide pyrophosphatase 1;plasma-cell membrane glycoprotein 1;plasma-cell membrane glycoprotein PC-1.
Similar products	ENPP1
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Polyclonal Antibodies/Growth Factors & Hormones, Root Catalog/Products/Monoclonal Antibodies/Drugs and Drug Metabolism, Root Catalog/Research Areas/Cell Biology, Root Catalog/Research Areas/Developmental Biology, Root Catalog/Research Areas/Immunology, Root Catalog/Research Areas/Stem Cells, Root Catalog/Research Areas/Immunohistochemistry, Root Catalog/Research Areas/Phosphorylation, Root Catalog/Research Areas/Cell Differentiation, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	105
Species Tested	Human
Application Data	This antibody has been successfully used in Western blot and IHC: Lau WM, Doucet M, Stadel R, Huang D, Weber KL, Kominsky SL Enpp1: a potential facilitator of breast cancer bone metastasis. PLoS One. 2013 Jul 5; 8(7):e66752. PMID: 23861746 This antibody has been successfully used in Western blot: SimÃ£o AM, Yadav MC, Narisawa S, Bolean M, Pizauro JM, Hoylaerts MF, Ciancaglini P, MillÃ¡n JL. Proteoliposomes harboring alkaline phosphatase and nucleotide pyrophosphatase as matrix vesicle biomimetics. J Biol Chem. 2010 Mar 5; 285(10):7598-609. PMID: 20048161.
Manufacturer - Application Additional Information	P-ELISA: Antibody detection limit dilution 1:32000 IHC: Paraffin embedded Human Thyroid Gland. Recommended concentration: 8 ug/mL.
Gene symbol	ENPP1
Gene Fullname	ectonucleotide pyrophosphatase/phosphodiesterase 1
Product format	Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20Â°C. Minimize freezing and thawing.
Reconstitution and storage	Aliquot and store at -20°C. Minimize freezing and thawing.
Protein accession_num	NP_006199.2
Protein name	Ectonucleotide pyrophosphatase/phosphodiesterase family member 1
Clonality	Polyclonal
Purification	Ammonium Sulfate Precipitated; Affinity Purified
Immunogen	ENPP1
Concentration	0.5 mg/ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 11/13/2025

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