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TINF2 Antibody - middle region

TINF2 Antibody - middle region

Item no.	ARP58338_P050
Manufacturer	AVIVA Systems Biology
Amount	100 ul
Category	Oncology Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Targets for Rodent Neurosciences Antibodies By Cell Type Carcinoma Hematology Lymphoma Myeloma Melanoma Sarcoma Mesothelioma Western Blot Primary Antibodies Astrocyte Markers
Type	Antibody Polyclonal
Format	Liquid
Applications	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Guinea Pig, Dog (Canine, Canis lupus familiaris), Horse (Equine), Pig (Porcine, Sus scrofa domesticus), Cow (Bos taurus)
Host	Rabbit
Sequence	SDEEENGQGEGKESLENYQKTKFDTLIPTLCEYLPPSGHGAIPVSSCDCR
Citations	Kim,S.H., (2008) J. Cell Biol. 181 (3), 447-460
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	TIN2,DKCA3
Similar products	TINF2
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Polyclonal Antibodies/Various, Root Catalog/Research Areas/DNA Damage & Repair, Root Catalog/Products/Polyclonal Antibodies/Trial Size Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies, Root Catalog/Products/Aviva Rabbit Polyclonal
Shipping Temperature	Wet Ice
Molecular Weight	50kDa
Species Tested	Human
Gene symbol	TINF2
Gene Fullname	TERF1 (TRF1)-interacting nuclear factor 2
Protein size	451
Product format	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and storage	For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Partner proteins	ACD; TERF2; TPP1; ANXA8L1; TNKS; TERF1; VIPR1; ZNF790; PAGE2; TUBB; DHFRL1; APOBEC3F; REM2; NUDCD2; CCDC43; SCRN2; TRIM15; TXNDC17; AFAP1L2; FERMT3; KCTD17; ANKMY2; PPP6R3; PGM2; APPL2; BIN2; LGALSL; PHPT1; GNMT; OR2H1; CCDC9; POT1; AIPL1; NCDN; ACOT7; TO
Description of target	TINF2 is a component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. It plays a role in shelterin complex assembly.
Nucleotide accession_num	NM_001099274
Protein accession_num	NP_001092744
Protein name	TERF1-interacting nuclear factor 2
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	The immunogen is a synthetic peptide directed towards the middle region of human TINF2
Homology	Cow: 100%; Dog: 86%; Guinea Pig: 92%; Horse: 93%; Human: 100%; Mouse: 92%; Pig: 100%; Rat: 85%
Concentration	0.5 mg/ml
Sample Type Confirmation	TINF2 is supported by BioGPS gene expression data to be expressed in MCF7

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 1/8/2026

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