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SIN3B antibody - middle region (ARP50589_P050)

SIN3B antibody - middle region (ARP50589_P050)

Item no.	ARP50589_P050
Manufacturer	AVIVA Systems Biology
Amount	100ul
Category	Neuroscience Neural Lineage Markers Metabolism Glucose Homeostasis Aging & Neurological Disorders Neural Epigenetics Antibodies Western Blot Primary Antibodies Glial Cell Markers
Type	Antibody Polyclonal
Format	Lyophilized powder
Applications	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Porcine, Rabbit (Oryctolagus cuniculus), Guinea Pig, Bovine, Canine, Equine
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	KIAA0700
Similar products	SIN3B
Available
Gene symbol	SIN3B
Protein name	Paired amphipathic helix protein Sin3b
Protein size	1162
Molecular weight	133kDa
Product format	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Gene id	23309
Reconstitution and storage	For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Partner proteins	SOX2. HDAC1. HDAC2. UBC. ESR1. AR. TFAP4. TP53. SUMO2. KLF16. MORF4L1. MORF4L2. MRGBP. KDM5A. CIITA. NR1D2. COPS2. SMN1. PBX1. REST. ZBTB4. ARID4A. MYT1. MXI1. SAP25. SMARCE1. SMARCB1. SMARCA4. SMARCA2. CBFA2T3. RNF220. ZBTB16. SETDB1. HDAC9. IKZF4. IKZF1
Description of target	SIN3B acts as a transcriptional repressor. It interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities.It also interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. SIN3B also forms a complex with FOXK1 which represses transcription.
Homology	Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 86%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 93%; Rat: 93%
Purification	Affinity Purified
Clonality	Polyclonal
Immunogen	The immunogen is a synthetic peptide directed towards the middle region of human SIN3B
Drywet	Wet Ice

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ul

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Delivery expected until 10/9/2025

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