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Goat Anti-CRHR1 / CRF-R (aa 107 - 117) Antibody

Goat Anti-CRHR1 / CRF-R (aa 107 - 117) Antibody

Item no.	OAEB02329
Manufacturer	AVIVA Systems Biology
Amount	100 ug
Category	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Molecular Targets for Neuroscience Antibodies By Cell Type Carcinoma Hematology Leukemia Lymphoma Western Blot Immunofluorescence Immunocytochemistry Cardiovascular Research Atherosclerosis Primary Antibodies Immunochemistry
Type	Antibody Polyclonal
Applications	WB, IF, ICC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Caprine
Sequence	C-NEEKKSKVHYH
Citations	Control of locomotor speed, arousal, and hippocampal theta rhythms by the nucleus incertus. Nat Commun. 11, 262 (2020). 31937768 * Rissman RA, Lee KF, Vale W, Sawchenko PE.; Corticotropin-releasing factor receptors differentially regulate stress-induced tau phosphorylation.; J Neurosci. 2007 Jun 13;27(24):6552-62.; Pubmed 17567816
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	corticotrophin releasing hormone receptor 1;corticotropin releasing hormone 1;corticotropin-releasing factor receptor 1;corticotropin-releasing factor type 1 receptor;CRF;CRF 1 receptor;CRF1;CRF1R;CRF-R;CRFR1;CRFR-1;CRF-R1;CRF-R-1;CRF-R1alpha;Crhr;CRH-R 1;CRH-R1;CRH-R-1;CRHR1L;seven transmembrane helix receptor.
Similar products	CRHR1
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Research Areas/Cell Biology, Root Catalog/Research Areas/Immunology, Root Catalog/Research Areas/Stem Cells, Root Catalog/Research Areas/GPCR, Root Catalog/Research Areas/Hypoxia, Root Catalog/Research Areas/Cell Differentiation, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	47, 7
Species Tested	Human, Mouse, Rat
Application Data	This antibody has been successfully used in ICC/IF on Rat: Zhong Xie, Peter Penzes, Deepak P. Srivastava EPAC2 is required for corticotropin-releasing hormone-mediated spine loss April 2019: doi: https://doi.org/10.1101/607598 PMID: 0 This antibody has been successfully used in Western blot on Mouse: Baglietto-Vargas D, Chen Y, Suh D, Ager RR, Rodriguez-Ortiz CJ, Medeiros R, Myczek K, Green KN, Baram TZ, LaFerla FM. Short-term modern life-like stress exacerbates A-beta-pathology and synapse loss in 3xTg-AD mice. J Neurochem. 2015 Sep; 134(5):915-26. PMID: 26077803 This antibody has been successfully used in Western blot on Mouse: Weerachayaphorn J, Mennone A, Soroka CJ, Harry K, Hagey LR, Kensler TW, Boyer JL. Nuclear factor-E2-related factor 2 is a major determinant of bile acid homeostasis in the liver and intestine. Am J Physiol Gastrointest Liver Physiol. 2012 May 1; 302(9):G925-36. PMID: 22345550 This antibody has been successfully used in IHC on Mouse: Jungling K, Liu X, Lesting J, Coulon P, Sosulina L, Reinscheid RK, Pape HC. Activation of neuropeptide S expressing neurons in the locus coeruleus by corticotropin-releasing factor. J Physiol. 2012 May 8. PMID: 22570383.
Manufacturer - Application Additional Information	P-ELISA: Antibody detection limit dilution 1:128000 WB: Approx 60 kDa band observed in Human Brain (Cerebellum), Colon, Rat Brain and Mouse spinal cord lysates (calculated MW of 47.7 kDa according to NP_004373.2). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Xu et al, Mol Pharmacol. 2001 Mar; 59(3):485-92; PMID: 11179443). Recommended concentration: 0.1-0.3 ug/ml. Primary incubation was 1 hour.
Gene symbol	Crhr1\|CRHR1
Gene Fullname	corticotropin releasing hormone receptor 1
Product format	Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20Â°C. Minimize freezing and thawing.
Reconstitution and storage	Aliquot and store at -20°C. Minimize freezing and thawing.
Protein accession_num	NP_004373.2
Protein name	Corticotropin-releasing factor receptor 1
Clonality	Polyclonal
Purification	Ammonium Sulfate Precipitated; Affinity Purified
Immunogen	CRHR1
Concentration	0.5 mg/ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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