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PUF60 antibody - C-terminal region (ARP40760_P050)

PUF60 antibody - C-terminal region (ARP40760_P050)

Item no.	ARP40760_P050
Manufacturer	AVIVA Systems Biology
Amount	100ul
Category	Oncology Neuroscience Neural Lineage Markers Metabolism Glucose Homeostasis Molecular Targets for Neuroscience Targets for Rodent Neurosciences Antibodies Immunohistochemistry Western Blot Primary Antibodies By Organ Renal Cancer Stem Cell Markers
Type	Antibody Polyclonal
Format	Lyophilized powder
Applications	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Fish, Guinea Pig, Bovine, Canine, Equine
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	FIR, FLJ31379, RoBPI, SIAHBP1
Similar products	PUF60
Available
Gene symbol	PUF60
Protein name	Poly(U)-binding-splicing factor PUF60
Protein size	542
Molecular weight	58kDa
Product format	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Gene id	22827
Reconstitution and storage	For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Partner proteins	ZG16. ARL8A. LOH12CR1. KIAA1683. MED28. QRICH1. UBE2I. SIAH1. SRSF11. SAP30BP. UPF2. KIAA0907. PUF60. U2AF2. SDCBP. RAD23B. CCNC. SUMO2. SUMO3. CDKN1A. UBC. ERG. EED. H3F3A. FAM129B. VPS29. FAF1. PAPOLA. NUDC. HIRIP3. ZYX. UGP2. TARS. TROVE2. PPM1G. PPP1R
Description of target	PUF60 is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription.The protein encoded by this gene is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription. This gene is implicated in the xeroderma pigmentosum disorder. There are two alternatively spliced transcript variants of this gene encoding different isoforms. There seems to be evidence of multiple polyadenylation sites for this gene.The protein encoded by this gene is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription. This gene is implicated in the xeroderma pigmentosum disorder. There are two alternatively spliced transcript variants of this gene encoding different isoforms. There seems to be evidence of multiple polyadenylation sites for this gene.
Homology	Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 100%
Purification	Affinity Purified
Clonality	Polyclonal
Immunogen	The immunogen is a synthetic peptide directed towards the C terminal region of human PUF60
Drywet	Wet Ice

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ul

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Delivery expected until 10/9/2025

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