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NLK antibody - middle region (ARP56863_P050)

NLK antibody - middle region (ARP56863_P050)

Item no.	ARP56863_P050
Manufacturer	AVIVA Systems Biology
Amount	100ul
Category	Oncology Neuroscience Neural Lineage Markers Neural Transcription Factors Molecular Targets for Neuroscience Aging & Neurological Disorders Neural Adhesion Molecules Antibodies Western Blot Primary Antibodies By Organ Bone Cancer
Type	Antibody Polyclonal
Format	Lyophilized powder
Applications	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Porcine, Rabbit (Oryctolagus cuniculus), Fish, Guinea Pig, Bovine, Canine, Equine
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	DKFZp761G1211, FLJ21033
Similar products	NLK
Available
Gene symbol	NLK
Protein name	Serine/threonine-protein kinase NLK
Protein size	527
Molecular weight	58kDa
Product format	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Gene id	51701
Reconstitution and storage	For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Partner proteins	KRTAP5-6. KRTAP10-3. KRTAP4-2. QRICH1. ZHX3. KRTAP5-9. GRN. TP53. MDM2. STAT5A. LEF1. CNOT2. SMAD4. KPNB1. BACH1. TNKS1BP1. FAM222A. C2orf44. CEP97. RNF219. FAM222B. CNOT11. NLK. PASK. SHANK2. UBAP2L. CCP110. TRPS1. TLE3. SKI. RANGAP1. RANBP2. PKM. CNOT3.
Description of target	NLK has a role in cell fate determination, required for differentiation of bone marrow stromal cells. NLK acts downstream of MAP3K7 and HIPK2 to negatively regulate the canonical Wnt/beta-catenin signaling pathway and the phosphorylation and destruction of the MYB transcription factor. NLK may suppress a wide range of transcription factors by phosphorylation of the coactivator, CREBBP By similarity.NLK is involved in TGFbeta-mediated mesoderm induction, acting downstream of MAP3K7/TAK1 to phosphorylate STAT3.
Homology	Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 93%
Purification	Affinity Purified
Clonality	Polyclonal
Immunogen	The immunogen is a synthetic peptide directed towards the middle region of human NLK
Drywet	Wet Ice

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ul

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Delivery expected until 10/9/2025

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