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IL6ST Antibody - middle region

IL6ST Antibody - middle region

Item no.	ARP63223_P050
Manufacturer	AVIVA Systems Biology
Amount	100 ul
Category	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Metabolism Diabetes Glucose Homeostasis Regulation of Appetite Neural Transcription Factors Molecular Targets for Neuroscience Neural Signaling Antibodies By Cell Type Carcinoma Hematology Leukemia Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis Immunohistochemistry Western Blot Primary Antibodies By Organ Heart & Blood Cancer Glial Cell Markers
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IHC
Specific against	Human (Homo sapiens), Rat (Rattus norvegicus), Rabbit (Oryctolagus cuniculus), Guinea Pig, Dog (Canine, Canis lupus familiaris), Horse (Equine), Cow (Bos taurus)
Host	Rabbit
Sequence	FTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKV
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CD130,GP130,HIES4,CDW130,IL-6RB,sGP130
Similar products	IL6ST
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Polyclonal Antibodies/Signaling Intermediate, Root Catalog/Products/Polyclonal Antibodies/Membrane Protein, Root Catalog/Research Areas/Immunology, Root Catalog/Research Areas/Disease Related, Root Catalog/Research Areas/Phosphorylation, Root Catalog/Products/Polyclonal Antibodies/Trial Size Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies, Root Catalog/Products/Aviva Rabbit Polyclonal
Shipping Temperature	Wet Ice
Molecular Weight	35kDa
Species Tested	Human
Gene symbol	IL6ST
Gene Fullname	Interleukin 6 signal transducer (gp130, oncostatin M receptor)
Protein size	329
Product format	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and storage	For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Partner proteins	SGTB; KCNIP3; UBQLN1; UBC; MAGEA11; SOCS3; PTPN11; IL31RA; CDK9; LIF; OSMR; PIK3CG; IL6ST; CTF1; TLE1; AR; ERBB3; PRKCD; TYK2; PTPN6; PLAUR; OSM; VAV1; ERBB2; LIFR; IL6R; JAK1; IL6; HCK; CNTFR; CNTF; STAT3; SHC1; PIK3R1; JAK2; GRB2;
Description of target	The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis.
Subunit	beta
Nucleotide accession_num	NM_175767
Protein accession_num	NP_786943
Protein name	Interleukin-6 receptor subunit beta
Clonality	Polyclonal
Purification	Affinity Purified
Homology	Cow: 93%; Dog: 93%; Guinea Pig: 86%; Horse: 86%; Human: 100%; Rabbit: 77%; Rat: 86%
Concentration	0.5 mg/ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 12/11/2025

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