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NR4A1 Antibody - N-terminal region

NR4A1 Antibody - N-terminal region

Item no.	ARP31941_T100
Manufacturer	AVIVA Systems Biology
Amount	100 ul
Category	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Metabolism Diabetes Molecular Targets for Neuroscience Aging & Neurological Disorders Antibodies By Cell Type Blastoma Immunohistochemistry Western Blot Primary Antibodies By Organ Thyroid Cancer Macrophage Markers
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Rabbit (Oryctolagus cuniculus), Guinea Pig, Dog (Canine, Canis lupus familiaris), Horse (Equine), Cow (Bos taurus)
Host	Rabbit
Sequence	GTPAPSPGPRDHLASDPLTPEFIKPTMDLASPEAAPAAPTALPSFSTFMD
Citations	Nuclear Receptor Nur77 Facilitates Melanoma Cell Survival under Metabolic Stress by Protecting Fatty Acid Oxidation. Mol Cell. 69, 480-492.e7 (2018). 29395065 Nur77 suppresses hepatocellular carcinoma via switching glucose metabolism toward gluconeogenesis through attenuating phosphoenolpyruvate carboxykinase sumoylation. Nat Commun. 8, 14420 (2017). 28240261 Lu,L., et al., (2004) J. Clin. Endocrinol. Metab. 89 (8), 4113-4118
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	HMR,N10,TR3,NP10,GFRP1,NAK-1,NGFIB,NUR77
Similar products	NR4A1
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Polyclonal Antibodies/Transcription Factor, Root Catalog/Products/Polyclonal Antibodies/Transcription Regulation, Root Catalog/Research Areas/Chromatin & Nuclear Signaling, Root Catalog/Research Areas/Apoptosis, Root Catalog/Research Areas/Receptors, Root Catalog/Products/Polyclonal Antibodies/Trial Size Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies, Root Catalog/Products/Aviva Rabbit Polyclonal
Shipping Temperature	Wet Ice
Molecular Weight	66kDa
Species Tested	Human
Gene symbol	NR4A1
Gene Fullname	Nuclear receptor subfamily 4, group A, member 1
Protein size	598
Product format	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and storage	For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Partner proteins	KRTAP10-5; KRTAP10-1; LONRF1; PGBD1; BCL2L10; CDKN2D; BCL2A1; BCL2; TUBB4A; VASP; ANKIB1; CUTA; NFKB1; SMAD3; LSS; HADHA; GLUD1; GK; CPT1A; SERPING1; ABCC6; ABCC13; SOCS4; ABCG8; DIABLO; HCVgp1; ABCA5; CHEK2; SUGT1; PRDX4; PRDX6; CHD1L; ABCB11; ARHGEF5; U
Description of target	NR4A1 encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis.
Nucleotide accession_num	NM_173157
Protein accession_num	NP_775180
Protein name	Nuclear receptor subfamily 4 group A member 1
Clonality	Polyclonal
Purification	Protein A purified
Immunogen	The immunogen is a synthetic peptide directed towards the N terminal region of human NR4A1
Homology	Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 92%; Rabbit: 93%; Rat: 93%
Concentration	1.0 mg/ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 11/27/2025

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