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CEBPA Antibody - N-terminal region

CEBPA Antibody - N-terminal region

Item no.	P100908_P050
Manufacturer	AVIVA Systems Biology
Amount	100 ul
Category	Oncology Neuroscience Neural Lineage Markers Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Regulation of Appetite Targets for Rodent Neurosciences Aging & Neurological Disorders Neural Signaling Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Western Blot Primary Antibodies Glial Cell Markers Neuronal Cell Markers
Type	Antibody Polyclonal
Format	Liquid
Applications	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Guinea Pig, Pig (Porcine, Sus scrofa domesticus), Cow (Bos taurus)
Host	Rabbit
Sequence	GGICEHETSIDISAYIDPAAFNDEFLADLFQHSRQQEKAKAAVGPTGGGG
Citations	Zhu,Q.S., et al., (2004) J. Biol. Chem. 279 (29), 29902-29910
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CEBP,C/EBP-alpha
Similar products	CEBPA
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Polyclonal Antibodies/Transcription Factor, Root Catalog/Products/Monoclonal Antibodies/Drugs and Drug Metabolism, Root Catalog/Research Areas/Cell Biology, Root Catalog/Research Areas/Pathways In Cancer, Root Catalog/Research Areas/Transcription Factors, Root Catalog/Research Areas/Cell Differentiation, Root Catalog/Products/Polyclonal Antibodies/Trial Size Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies, Root Catalog/Products/Aviva Rabbit Polyclonal, Root Catalog/Research Areas/Cancer/Cancer Transcription Factor
Shipping Temperature	Wet Ice
Molecular Weight	38kDa
Species Tested	Human
Gene symbol	CEBPA
Gene Fullname	CCAAT/enhancer binding protein (C/EBP), alpha
Protein size	358
Product format	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and storage	For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Partner proteins	CEBPB; ZBTB16; RARA; HDAC1; BHLHE41; UBC; CEBPE; BATF2; BATF3; YY1AP1; ATF5; BATF; FOSL1; FOS; DBP; CEBPG; CEBPA; ATF4; ATF3; UBE3A; SKP2; RASGRF1; C1QBP; CDKN1A; SRA1; CDK4; PIAS1; Fbxw7; GRIN3A; RAB34; NAA16; POLR1E; MRTO4; AK5; MACF1; KAT5; AKAP9; SMC1
Description of target	CEBPA is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. It has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, CEBPA can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.
Nucleotide accession_num	NM_004364
Protein accession_num	NP_004355
Protein name	CCAAT/enhancer-binding protein alpha
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	The immunogen is a synthetic peptide directed towards the N terminal region of human CEBPA
Homology	Cow: 100%; Guinea Pig: 90%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%
Concentration	0.5 mg/ml
Sample Type Confirmation	CEBPA is supported by BioGPS gene expression data to be expressed in HepG2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 11/27/2025

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