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FMR1 Antibody

FMR1 Antibody

Item no.	OAEB01228
Manufacturer	AVIVA Systems Biology
Amount	100 ug
Category	Neuroscience Neural Transcription Factors Molecular Targets for Neuroscience Antibodies Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Dog (Canine, Canis lupus familiaris)
Host	Caprine
Purity	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Sequence	C-RTGKDRNQKKEKPD
Citations	Nuclear Fragile X Mental Retardation Protein is localized to Cajal bodies. PLoS Genet. 9, e1003890 (2013). 24204304 * Hanson JE, Blank M, Valenzuela RA, Garner CC, Madison DV.; The functional nature of synaptic circuitry is altered in area CA3 of the hippocampus in a mouse model of Down's syndrome.; J Physiol. 2007 Feb 15;579(Pt 1):53-67. Epub 2006 Dec 7.; Pubmed 17158177
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	FMRP;fragile X mental retardation 1;fragile X mental retardation protein 1;FRAXA;POF;POF1;synaptic functional regulator FMR1;truncated FMRP.
Similar products	FMR1
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Polyclonal Antibodies/RNA Binding Proteins, Root Catalog/Research Areas/Developmental Biology, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	71, 2
Manufacturer - Application Additional Information	Peptide ELISA: antibody detection limit dilution 1:128000. Western Blot: Approx 80kDa band observed in lysates of cell line KELLY (calculated MW of 71.2kDa according to NP_002015.1). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Sittler et al, Hum Mol Genet. 1996 Jan; 5(1):95-102; PMID: 8789445). Recommended concentration: 0.1-0.3ug/ml.
Gene symbol	FMR1
Gene Fullname	FMRP translational regulator 1
Product format	Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20Â°C. Minimize freezing and thawing.
Reconstitution and storage	Aliquot and store at -20C. Minimize freezing and thawing.
Protein accession_num	NP_002015.1
Protein name	Fragile X mental retardation protein 1
Clonality	Polyclonal
Purification	Ammonium Sulfate Precipitated; Affinity Purified
Immunogen	FMR1
Homology	Cow: 92%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Concentration	0.5 mg/ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 12/11/2025

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