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PAXIP1 antibody - N-terminal region (ARP51642_P050)

PAXIP1 antibody - N-terminal region (ARP51642_P050)

Item no.	ARP51642_P050
Manufacturer	AVIVA Systems Biology
Amount	100ul
Category	Oncology Antibodies By Cell Type Western Blot Primary Antibodies By Organ Renal Cancer
Type	Antibody Polyclonal
Format	Lyophilized powder
Applications	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Rabbit (Oryctolagus cuniculus), Fish, Guinea Pig, Bovine, Canine, Equine
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	PTIP, TNRC2, CAGF28, CAGF29, PACIP1, PAXIP1L, FLJ41049
Similar products	PAXIP1
Available
Gene symbol	PAXIP1
Protein name	PAX-interacting protein 1
Protein size	697
Molecular weight	74kDa
Product format	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Gene id	22976
Reconstitution and storage	For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Partner proteins	MAPRE2. POM121. NXT1. PPARG. XAGE1E. SMAD2. SPATA18. COMTD1. BTBD16. DIS3L. LACTB. HNRNPLL. ZNF251. ZNF622. BTBD6. C7orf50. FAM175A. TMEM120A. FAHD1. TM2D3. ATHL1. CENPU. DYNC2H1. BRCC3. KRI1. ANAPC1. NOM1. POLR1E. NCAPG. AASDHPPT. RBM25. CATSPERG. WDR48.
Description of target	PAXIP1 functions as a key component of the DNA damage response, and phosphoserine or phosphothreonine-specific binding modules. PAXIP1 recognizes substrates phosphorylated by the kinases ataxia telangiectasia-mutated (ATM), ataxia telangiectasia and RAD3-related (ATR) in response to gamma irradiation. It may play a role in PAX2-dependent transcriptional regulation. PAXIP1 plays a role in early development, most probably in cell proliferation.
Homology	Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%
Purification	Affinity Purified
Clonality	Polyclonal
Immunogen	The immunogen is a synthetic peptide directed towards the N terminal region of human PAXIP1
Drywet	Wet Ice

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ul

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Delivery expected until 10/9/2025

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