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HDAC9 Antibody - C-terminal region

HDAC9 Antibody - C-terminal region

Item no.	ARP42788_T100
Manufacturer	AVIVA Systems Biology
Amount	100 ul
Category	Oncology Neuroscience Neural Epigenetics Antibodies Immunohistochemistry Immunoprecipitation Western Blot Primary Antibodies CHiP By Organ Heart & Blood Cancer
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IHC, CHIP
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Guinea Pig, Sheep (Ovine, Ovis aries)
Host	Rabbit
Sequence	QVGAVKVKEEPVDSDEDAQIQEMESGEQAAFMQQVIGKDLAPGFVIKVII
Citations	Hang, C. T. et al. Chromatin regulation by Brg1 underlies heart muscle development and disease. Nature 466, 62-7 (2010). 20596014 Milde, T. et al. HDAC5 and HDAC9 in medulloblastoma: novel markers for risk stratification and role in tumor cell growth. Clin. Cancer Res. 16, 3240-52 (2010). 20413433 Spallotta, F. et al. Detrimental effect of class-selective histone deacetylase inhibitors during tissue regeneration following hindlimb ischemia. J. Biol. Chem. 288, 22915-29 (2013). 23836913 Han,A., (2005) J. Mol. Biol. 345 (1), 91-102
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	HD7,HD9,HD7b,HDAC,HDRP,MITR,HDAC7,HDAC7B,HDAC9B,HDAC9FL
Similar products	HDAC9
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Polyclonal Antibodies/Cell Cycle Proteins, Root Catalog/Products/Polyclonal Antibodies/Lymphocyte Signaling, Root Catalog/Research Areas/Chromatin & Nuclear Signaling, Root Catalog/Research Areas/Developmental Biology, Root Catalog/Research Areas/Epigenetics, Root Catalog/Research Areas/Meiosis\/Mitosis\/Cell Cycle, Root Catalog/Research Areas/Immunohistochemistry, Root Catalog/Research Areas/Chromatin Immunoprecipitation, Root Catalog/Research Areas/Acetylation, Root Catalog/Research Areas/Transcription Factors, Root Catalog/Research Areas/Cell Differentiation, Root Catalog/Products/Polyclonal Antibodies/Trial Size Polyclonal Antibodies, Root Catalog/Products/Polyclonal Antibodies/Enhanced Validation Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies, Root Catalog/Products/Aviva Rabbit Polyclonal
Shipping Temperature	Wet Ice
Molecular Weight	65 kDa
Species Tested	Human
Gene symbol	HDAC9
Gene Fullname	Histone deacetylase 9
Protein size	590
Product format	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and storage	For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Partner proteins	NOP2; MKI67; EIF6; RCC1; ADAR; TOP1; TMPO; FIP1L1; CCAR2; TPX2; RBM14; ZC3H11A; HDAC9; NUP93; SMC3; H1FX; TPR; HINT1; CTBP1; BCL6; Zfp521; TRIM29; TP53; MAML1; SMARCA4; PARP1; CEBPB; H3F3A; RL2; CAMK1; YWHAE; HDAC1; SFN; MEF2B; ANKRA2; RFXANK; PKD1; SYK;
Description of target	Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC9 has sequence homology to members of the histone deacetylase family. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. HDAC9 may play a role in hematopoiesis.Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to the Xenopus and mouse MITR genes. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. This encoded protein may play a role in hematopoiesis. Multiple alternatively spliced transcripts have been described for this gene but the full-length nature of some of them has not been determined.
Nucleotide accession_num	NM_014707
Protein accession_num	NP_055522
Protein name	Histone deacetylase 9
Clonality	Polyclonal
Purification	Protein A purified
Immunogen	The immunogen is a synthetic peptide directed towards the C terminal region of human HDAC9
Homology	Guinea Pig: 100%; Human: 100%; Mouse: 100%; Sheep: 100%
Concentration	1.0 mg/ml
Sample Type Confirmation	HDAC9 is supported by BioGPS gene expression data to be expressed in A172

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 10/30/2025

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