LILRA5 Antibody - N-terminal region (ARP66847_P050)

Leukocyte immunoglobulin-like receptor subfamily A member 5

29kDa

353514

The protein encoded by this gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family. LIR family members are known to have activating and inibitory functions in leukocytes. Crosslink of this receptor protein on the surface of monocytes has been shown to induce calcium flux and secretion of several proinflammatory cytokines, which suggests the roles of this protein in triggering innate immune responses. This gene is one of the leukocyte receptor genes that form a gene cluster on the chromosomal region 19q13.4. Four alternatively spliced transcript variants encoding distinct isoforms have been described.

Affinity Purified

The immunogen is a synthetic peptide directed towards the N-terminal region of Human LILRA5