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FBXL15 Antibody - N-terminal region (ARP70412_P050)

FBXL15 Antibody - N-terminal region (ARP70412_P050)

Item no.	ARP70412_P050
Manufacturer	AVIVA Systems Biology
Amount	100ul
Category	Antibodies Western Blot Primary Antibodies
Type	Antibody Polyclonal
Format	Lyophilized powder
Applications	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Rabbit (Oryctolagus cuniculus), Bovine, Canine, Equine, Goat (Caprine, Capra aegagrus hircus)
Host	Rabbit
Protein Family	COPS6,CUL1,SKP1,UBC
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	FBXO37, Fbl15, JET, PSD
Similar products	FBXO37, Fbl15, JET, PSD
Available
Gene symbol	FBXL15
Protein name	F-box/LRR-repeat protein 15
Protein size	300
Molecular weight	32kDa
Product format	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Gene id	79176
Reconstitution and storage	For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Partner proteins	HNRNPD. SKP1. ITCH. SMURF2. HECW2. SMURF1. NEDD4L. HECW1. WWP2. WWP1. RBX1. CUL1. NEDD4. HSP90AA1. COPS6. UBC.
Description of target	FBXL15 is a substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SMURF1, thereby acting as a positive regulator of the BMP signaling pathway. It is required for dorsal/ventral pattern formation and bone mass maintenance and also mediates ubiquitination of SMURF2 and WWP2.
Homology	Cow: 93%; Dog: 100%; Goat: 93%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 86%; Rat: 93%
Purification	Affinity Purified
Clonality	Polyclonal
Immunogen	The immunogen is a synthetic peptide directed towards the N-terminal region of Human FBXL15
Drywet	Wet Ice

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ul

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Delivery expected until 8/28/2025

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