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FRS2 Antibody (Phospho-Tyr436)

FRS2 Antibody (Phospho-Tyr436)

Item no.	OAAF00503
Manufacturer	AVIVA Systems Biology
Amount	100 ug
Category	Oncology Neuroscience Molecular Targets for Neuroscience Targets for Rodent Neurosciences Neural Signaling Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Immunohistochemistry Western Blot ELISA Immunofluorescence Cardiovascular Research Myocardial Infarction Primary Antibodies By Organ Thyroid Cancer Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IF, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Monkey (Cynomolgus, Simian)
Host	Rabbit
Citations	Xu H., J. Biol. Chem. 273:17987-17990(1998). Meakin S.O., J. Biol. Chem. 274:9861-9870(1999). Dhalluin C., Mol. Cell 6:921-929(2000).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	epididymis secretory sperm binding protein;FGFR signalling adaptor;FGFR substrate 2;FGFR-signaling adaptor SNT;fibroblast growth factor receptor substrate 2;FRS1A;FRS2A;FRS2alpha;SNT;SNT1;SNT-1;suc1-associated neurotrophic factor target 1.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	Enzyme-linked immunosorbent assay\|Immunofluorescence\|Immunohistochemistry\|Immunohistochemistry-Paraffin\|Western blot
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Polyclonal Antibodies/Phospho Specific, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	57 kDa
Manufacturer - Application Additional Information	WB: 1:500~1:1000; IHC: 1:50~1:100; ELISA: 1:10000
Gene symbol	FRS2
Gene Fullname	fibroblast growth factor receptor substrate 2
Product format	Liquid
Reconstitution and storage	-20°C
Description of target	Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.
Protein accession_num	NP_001036020.1
Protein name	Fibroblast growth factor receptor substrate 2
Clonality	Polyclonal
Purification	The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Immunogen	The antiserum was produced against synthesized peptide derived from human FRS2 around the phosphorylation site of Tyr436.
Dilution	The optimal working dilution should be determined by the end user.
Manufacturer - Specificity	FRS2 (Phospho-Tyr436) antibody detects endogenous levels of FRS2 only when phosphorylated at tyrosine 436.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 11/13/2025

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