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IGFBP3 Antibody

IGFBP3 Antibody

Item no.	OAAF01118
Manufacturer	AVIVA Systems Biology
Amount	100 ug
Category	Metabolism Diabetes Antibodies Cell Biology Cell Status Immunohistochemistry Western Blot ELISA Immunofluorescence Senescence Primary Antibodies Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IF, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Citations	Wood W.I., Mol. Endocrinol. 2:1176-1185(1988). Cubbage M.L., J. Biol. Chem. 265:12642-12649(1990). Thweatt R., DNA Seq. 4:43-46(1993).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	acid stable subunit of the 140 K IGF complex;binding protein 29;binding protein 53;BP-53;growth hormone-dependent binding protein;IBP3;IBP-3;IGF-binding protein 3;IGFBP-3;insulin-like growth factor-binding protein 3.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	Enzyme-linked immunosorbent assay\|Immunofluorescence\|Immunohistochemistry\|Immunohistochemistry-Paraffin\|Western blot
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	31 kDa
Manufacturer - Application Additional Information	WB: 1:500~1000 IHC: 1:50~100 ELISA: 1:1000
Gene symbol	IGFBP3
Gene Fullname	insulin like growth factor binding protein 3
Product format	Liquid. PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Reconstitution and storage	-20°C
Description of target	IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R.
Protein accession_num	NP_000589.2
Protein name	Insulin-like growth factor-binding protein 3
Clonality	Polyclonal
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen	The antiserum was produced against synthesized peptide derived from human IGFBP-3.
Dilution	The optimal working dilution should be determined by the end user.
Manufacturer - Specificity	IGFBP-3 (Ab-183) antibody detects endogenous levels of total IGFBP-3 protein.
Concentration	1 mg/ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 11/13/2025

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