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CARD14 Antibody

CARD14 Antibody

Item no.	OAAF02866
Manufacturer	AVIVA Systems Biology
Amount	100 ug
Category	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Antibodies By Cell Type Hematology Leukemia Lymphoma Myeloma Cell Biology Cell Status Apoptosis Immunohistochemistry ELISA Immunofluorescence Immunocytochemistry Primary Antibodies By Organ Immunostaining Lymphatic System Cancer Immunochemistry
Type	Antibody Polyclonal
Format	Liquid
Applications	IF, IHC, ICC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Citations	Bertin J., J. Biol. Chem. 276:11877-11882(2001). Gaide O., FEBS Lett. 496:121-127(2001). The MGC Project Team, ome Res. 14:2121-2127(2004).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	bcl10-interacting maguk protein 2;BIMP2;CARD-containing MAGUK protein 2;CARMA2;caspase recruitment domain-containing protein 14;PRP;PSORS2;PSS1.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	Enzyme-linked immunosorbent assay\|Immunocytochemistry\|Immunofluorescence\|Immunohistochemistry-Paraffin
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	113 kDa
Manufacturer - Application Additional Information	IF: 1:100~1:500; ELISA: 1:40000
Gene symbol	CARD14
Gene Fullname	caspase recruitment domain family member 14
Product format	Liquid
Reconstitution and storage	-20°C
Description of target	Acts as a scaffolding protein that can activate the inflammatory transcription factor NF-kappa-B and p38/JNK MAP kinase signaling pathways. Forms a signaling complex with BCL10 and MALT1, and activates MALT1 proteolytic activity and inflammatory gene expression. MALT1 is indispensable for CARD14-induced activation of NF-kappa-B and p38/JNK MAP kinases (PubMed:11278692, PubMed:21302310, PubMed:27113748, PubMed:27071417). May play a role in signaling mediated by TRAF2, TRAF3 and TRAF6 and protects cells against apoptosis.
Protein accession_num	NP_001244899.1
Protein name	Caspase recruitment domain-containing protein 14
Clonality	Polyclonal
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen	The antiserum was produced against synthesized peptide derived from human CAR14.
Dilution	The optimal working dilution should be determined by the end user.
Manufacturer - Specificity	CAR14 antibody detects endogenous levels of total CAR14 protein.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 1/29/2026

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