Comparison

CD59 antibody (OAEE00287)

Item no. OAEE00287
Manufacturer AVIVA Systems Biology
Amount 0.1 mg
Category
Type Antibody Monoclonal
Applications WB, FC, IP, IHC
Clone MEM-43/5
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Mouse
Isotype IgG2b
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias CD59
Similar products CD59
Available
Gene symbol
CD59
Protein name
CD59 glycoprotein
Product format
Liquid. PBS with 15mM sodium azide (approx. pH 7.4)
Gene id
966
Reconstitution and storage
Store at 2-8C. Do not freeze.
Description of target
CD59 (Protectin) is a small (18-20 kDa) GPI-anchored ubiquitously expressed inhibitor of the membrane attack complex (MAC). It is thus the key regulator that preserves the autologous cells from terminal effector mechanism of the complement cascade. CD59 associates with C5b-8 complex and thereby counteracts appropriate formation of cytolytic pore within the plasma membrane. CD59 is also an low-affinity ligand of human CD2 and causes T cell costimulation.
Purification
Purified from ascites by protein A affinity chromatography.
Clonality
Monoclonal
Immunogen
Thymocytes and T lymphocytes
Purity
> 95% (by SDS-PAGE)
Drywet
Wet Ice

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 0.1 mg
Available: In stock
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