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NR1I2 Antibody (OALA02244)

NR1I2 Antibody (OALA02244)

Item no.	OALA02244
Manufacturer	AVIVA Systems Biology
Amount	50 ul
Category	Food Safety Hormones Antibodies Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG kappa
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	NR1I2, BXR, Orphan nuclear receptor PXR, Orphan nuclear receptor PAR1, PARq, PRR, PXR, Pregnane X receptor, ONR1, SAR, SXR
Similar products	NR1I2, PXR, BXR, ONR1, PARq, PRR, SAR, SXR, Orphan nuclear receptor PAR1, Orphan nuclear receptor PXR, Pregnane X receptor
Available
Description	Pregnane X receptor (PXR), a NR1 Thyroid Hormone-Like Receptor, has been shown to mediate the effects of steroid hormones, including progesterone, glucocorticoid, and pregnenolone, and effects of xenobiotics, through the cytochrome P-450 3A gene family (CYP3A). PXR protects the body from hepatotoxicity of secondary bile acids such as lithocholic acid (LCA) by inducing expression of the hydroxylating cytochrome P450 enzyme CYP3A and promoting detoxification.
Gene symbol	NR1I2
Alias symbols	NR1I2, BXR, Orphan nuclear receptor PXR, Orphan nuclear receptor PAR1, PARq, PRR, PXR, Pregnane X receptor, ONR1, SAR, SXR
Gene_id	8856
Reconstitution and storage	Short term 4C, long term aliquot and store at -20C, avoid freeze thaw cycles.
Specificity	Recombinant (partial), N-terminal.
Purification	Immunoaffinity purified
Warning	For research use only.
Immunogen	NR1I2 / PXR / PAR antibody was raised against recombinant human NR1I2 / PXR.
Application Info	IHC - Paraffin (1:50), Western blot

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ul

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Delivery expected until 10/9/2025

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