« Back
Home /
SARM Antibody

SARM Antibody

Item no.	OAPB00233
Manufacturer	AVIVA Systems Biology
Amount	0.1 mg
Category	Oncology Neuroscience Neural Lineage Markers Antibodies By Cell Type Carcinoma Hematology Leukemia Lymphoma Western Blot ELISA Immunofluorescence Immunocytochemistry Primary Antibodies By Organ Bladder Cancer Immunostaining Glial Cell Markers Immunochemistry
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IF, ICC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Pig (Porcine, Sus scrofa domesticus)
Host	Rabbit
Conjugate/Tag	Unconjugated
Citations	Vogel SN, Fitzgerald KA, and Fenton MJ. TLRs: differential adapter utilization by toll-like receptors mediates TLR-specific patterns of gene expression. Mol. Interv. 2003; 3:466-77.;Takeda K, Kaisho T, and Akira S. Toll-like receptors. Annu. Rev. Immunol. 2003; 21:335-76.;Janeway CA Jr and Medzhitov R. Innate immune recognition. Annu. Rev. Immunol. 2002; 20:197-216.;Oâ€™Neill LAJ, Fitzgerald FA, and Bowie AG. The Toll-IL-1 receptor adaptor family grows to five members. Trends in Imm. 2003; 24:286-9.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	hSARM1;HsTIR;MyD88-5;NAD(+) hydrolase SARM1;NADase SARM1;NADP(+) hydrolase SARM1;SAM domain-containing protein 2;SAMD2;SARM;sterile alpha and Armadillo repeat protein;sterile alpha and HEAT/Armadillo motif protein,ortholog of Drosophila;sterile alpha and TIR motif-containing protein 1;sterile alpha motif domain-containing protein 2;tir-1 homolog.
Similar products	SARM
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	Predicted: 80 kDa Observed: 85 kDa
Manufacturer - Application Additional Information	SARM antibody can be used for detection of SARM by Western blot at 0.5 to 2 ug/ml. (Optimal dilution should be determined by user)
Gene symbol	SARM1
Gene Fullname	sterile alpha and TIR motif containing 1
Product format	Liquid. SARM Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution and storage	2°C to 8°C
Description of target	Negative regulator of MYD88- and TRIF-dependent toll-like receptor signaling pathway which plays a pivotal role in activating axonal degeneration following injury. Promotes Wallerian degeneration an injury-induced axonal death pathway which involves degeneration of an axon distal to the injury site. Can activate neuronal death in response to stress. Regulates dendritic arborization through the MAPK4-JNK pathway. Involved in innate immune response. Inhibits both TICAM1/TRIF- and MYD88-dependent activation of JUN/AP-1, TRIF-dependent activation of NF-kappa-B and IRF3, and the phosphorylation of MAPK14/p38.
Protein accession_num	https://www.ncbi.nlm.nih.gov/protein/NP_055892
Protein name	Sterile alpha and TIR motif-containing protein 1\|sterile alpha and TIR motif-containing protein 1 precursor [Homo sapiens]
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	SARM antibody was raised against a peptide corresponding to 14 amino acids near the C-terminus of human SARM. The immunogen is located within amino acids 640 - 690 of SARM.
Homology	Human; Mouse
Concentration	1 mg/ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

OAPB00233-datasheet.pdf

Request safety datasheet

Simple Order Order Subscription

Amount: 0.1 mg

available

Delivery expected until 11/27/2025

Express Delivery: Save 3 days

Compare

Add to wishlist

Get an offer