Comparison

RARA antibody - N-terminal region (ARP40314_P050)

Item no. ARP40314_P050
Manufacturer AVIVA Systems Biology
Amount 100ul
Category
Type Antibody Polyclonal
Format Lyophilized powder
Applications WB
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias NR1B1, RAR
Similar products RARA
Available
Gene symbol
RARA
Protein name
Retinoic acid receptor alpha
Protein size
457
Molecular weight
51kDa
Product format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Gene id
5914
Reconstitution and storage
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Partner proteins
NCOR2. NCOR1. RXRG. MED1. HDAC1. NRIP1. TEKT4. NSD1. NCOA1. CEBPA. ITGB1BP2. SUMO1. UBC. MBD3. CBX5. MTA2. E2F1. WWOX. Sumo2. RXRB. RXRA. AKT1. MMS19. Dlg4. TMEM54. FN1. USP7. NCOA2. SUZ12. EZH2. PML. PSMC5. FAS. PRAM1. TBL1XR1. PRAME. ARID5A. UBE3A. UBQL
Description of target
Retinoid signaling is transduced by 2 families of nuclear receptors, retinoic acid receptor (RAR) and retinoid X receptor, which form RXR/RAR heterodimers. In the absence of ligand, DNA-bound RXR/RARA represses transcription by recruiting the corepressors NCOR1, SMRT, and histone deacetylase. When ligand binds to the complex, it induces a conformational change allowing the recruitment of coactivators, histone acetyltransferases, and the basic transcription machinery.
Homology
Human: 100%; Mouse: 81%; Rat: 81%
Purification
Affinity Purified
Clonality
Polyclonal
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human RARA
Drywet
Wet Ice

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100ul
Available: In stock
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