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MAP3K1 Antibody (Phospho-Thr1402)

MAP3K1 Antibody (Phospho-Thr1402)

Item no.	OAAF00451
Manufacturer	AVIVA Systems Biology
Amount	100 ug
Category	Oncology Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Status Immunohistochemistry Western Blot ELISA Immunofluorescence Senescence Primary Antibodies Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IF, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Citations	Schmutz J., Nature 431:268-274(2004). Xia Y., Genes Dev. 12:3369-3381(1998). Vinik B.S., Mamm. Genome 6:782-783(1995)
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	MAP/ERK kinase kinase 1;MAPK/ERK kinase kinase 1;MAPKKK1;MEK kinase 1;MEKK;MEKK 1;MEKK1;mitogen-activated protein kinase kinase kinase 1;mitogen-activated protein kinase kinase kinase 1,E3 ubiquitin protein ligase;SRXY6.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	Enzyme-linked immunosorbent assay\|Immunofluorescence\|Immunohistochemistry\|Immunohistochemistry-Paraffin\|Western blot
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Polyclonal Antibodies/Phospho Specific, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	161 kDa
Manufacturer - Application Additional Information	WB 1:500~1000 IHC 1:50~100 ELISA 1:40000
Gene symbol	MAP3K1
Gene Fullname	mitogen-activated protein kinase kinase kinase 1
Product format	Liquid. PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Reconstitution and storage	-20°C
Description of target	Component of a protein kinase signal transduction cascade (PubMed:9808624). Activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4 (PubMed:9808624). May phosphorylate the MAPK8/JNK1 kinase (PubMed:17761173). Activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway (PubMed:9808624).
Protein accession_num	NP_005912.1
Protein name	Mitogen-activated protein kinase kinase kinase 1
Clonality	Polyclonal
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen	The antiserum was produced against synthesized peptide derived from human MAP3K1 around the phosphorylation site of Thr1402.
Dilution	The optimal working dilution should be determined by the end user.
Manufacturer - Specificity	MAP3K1 (Phospho-Thr1402) antibody detects endogenous levels of MAP3K1 only when phosphorylated at threonine 1402.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 11/13/2025

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