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CRK Antibody

CRK Antibody

Item no.	OAAF00679
Manufacturer	AVIVA Systems Biology
Amount	100 ug
Category	Oncology Neuroscience Neural Lineage Markers Antibodies By Cell Type Carcinoma Hematology Leukemia Myeloma Myelofibrosis Immunohistochemistry Western Blot ELISA Immunofluorescence Immunocytochemistry Primary Antibodies Immunostaining Stem Cell Markers Immunochemistry
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IF, IHC, ICC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Monkey (Cynomolgus, Simian)
Host	Rabbit
Citations	Robert F. Spurney, J. Clin. Invest., May 2002; 109: 1361. Faiyaz Ahmad, J. Immunol., Apr 1999; 162: 4864. Feng Liu, J. Biol. Chem., Dec 1996; 271: 31290. Jaap J. Van Hellemond, J. Biol. Chem., Mar 2000; 275: 8315.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	adapter molecule crk;CRKII;p38;proto-oncogene c-Crk;v-crk avian sarcoma virus CT10 oncogene homolog;v-crk sarcoma virus CT10 oncogene-like protein.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	Enzyme-linked immunosorbent assay\|Immunocytochemistry\|Immunofluorescence\|Immunohistochemistry\|Immunohistochemistry-Paraffin\|Western blot
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	33 kDa
Manufacturer - Application Additional Information	WB: 1:500~1:3000; IHC: 1:50~1:100; IF: 1:100~1:500; ELISA: 1:5000
Gene symbol	CRK
Gene Fullname	CRK proto-oncogene, adaptor protein
Product format	Liquid
Reconstitution and storage	-20°C
Description of target	Isoform Crk-II: Regulates cell adhesion, spreading and migration. Mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling.
Protein accession_num	NP_005197.3
Protein name	Adapter molecule crk
Clonality	Polyclonal
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen	The antiserum was produced against synthesized peptide derived from human CrkII.
Dilution	The optimal working dilution should be determined by the end user.
Manufacturer - Specificity	CrkII (Ab-221) antibody detects endogenous levels of total CrkII protein.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 1/29/2026

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