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RyR2 Antibody

RyR2 Antibody

Item no.	OAAF00837
Manufacturer	AVIVA Systems Biology
Amount	100 ug
Category	Oncology Neuroscience Molecular Targets for Neuroscience Antibodies Immunohistochemistry Western Blot ELISA Immunofluorescence Immunocytochemistry Primary Antibodies By Organ Colorectal Cancer Immunostaining Immunochemistry
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IF, IHC, ICC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Citations	Tunwell R.E.A., Biochem. J. 318:477-487(1996). Tiso N., Hum. Mol. Genet. 10:189-194(2001). Awad S.S., Biochem. J. 322:777-783(1997)
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ARVC2;ARVD2;Cardiac muscle ryanodine receptor;cardiac muscle ryanodine receptor-calcium release channel;cardiac-type ryanodine receptor;islet-type ryanodine receptor;kidney-type ryanodine receptor;ryanodine receptor 2;ryanodine receptor 2 (cardiac);RyR;RYR-2;type 2 ryanodine receptor;VACRDS;VTSIP.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	Enzyme-linked immunosorbent assay\|Immunocytochemistry\|Immunofluorescence\|Immunohistochemistry\|Immunohistochemistry-Paraffin\|Western blot
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	564 kDa
Manufacturer - Application Additional Information	IHC: 1:50~1:100; IF: 1:100~1:500; ELISA: 1:1000
Gene symbol	RYR2
Gene Fullname	ryanodine receptor 2
Product format	Liquid
Reconstitution and storage	-20°C
Description of target	Calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering cardiac muscle contraction. Aberrant channel activation can lead to cardiac arrhythmia. In cardiac myocytes, calcium release is triggered by increased Ca(2+) levels due to activation of the L-type calcium channel CACNA1C. The calcium channel activity is modulated by formation of heterotetramers with RYR3. Required for cellular calcium ion homeostasis. Required for embryonic heart development.
Protein accession_num	NP_001026.2
Protein name	Ryanodine receptor 2
Clonality	Polyclonal
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen	The antiserum was produced against synthesized peptide derived from human RyR2.
Dilution	The optimal working dilution should be determined by the end user.
Manufacturer - Specificity	RyR2 antibody detects endogenous levels of total RyR2 protein
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 1/29/2026

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