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BCL2 Antibody

BCL2 Antibody

Item no.	OAAF00934
Manufacturer	AVIVA Systems Biology
Amount	100 ug
Category	Oncology Neuroscience Neuroinflammation Metabolism Cholesterol & Lipid Metabolism Neural Signaling Antibodies By Cell Type Blastoma Carcinoma Hematology Leukemia Lymphoma Myeloma Cell Biology Cell Movement Cell Adhesion Cell Culture Cytokines Cell Status Apoptosis Immunohistochemistry Western Blot ELISA Immunofluorescence Immunocytochemistry Autophagy Cardiovascular Research Ischemia & Reperfusion Injury Primary Antibodies By Organ Colorectal Cancer Testicular & Prostate Cancer Immunostaining Lymphatic System Cancer Immunochemistry
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IF, IHC, ICC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Citations	Fibroblast growth factor 22 is a novel modulator of depression through interleukin-1ÃŽÂ². CNS Neurosci Ther. 23, 907-916 (2017). 28948716 H. Kurosawa, Am J Physiol Gastrointest Liver Physiol, Jun 1997; 272: 1587. JR Park, Blood, Aug 1995; 86: 868 - 876. A Plettenberg, Am. J. Pathol., Mar 1995; 146: 651. JM Ben-Ezra, Am. J. Pathol., Nov 1994; 145: 1036
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	apoptosis regulator Bcl-2;B-cell CLL/lymphoma 2;Bcl-2;PPP1R50;protein phosphatase 1,regulatory subunit 50.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	Enzyme-linked immunosorbent assay\|Immunocytochemistry\|Immunofluorescence\|Immunohistochemistry\|Immunohistochemistry-Paraffin\|Western blot
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies, Root Catalog/Research Areas/Cancer/Cancer Apoptosis
Shipping Temperature	Wet Ice
Molecular Weight	26 kDa
Manufacturer - Application Additional Information	WB: 1:500~1000 IHC: 1:50~100 IF: 1:100~500 ELISA: 1:10000
Gene symbol	BCL2
Gene Fullname	BCL2 apoptosis regulator
Product format	Liquid. PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Reconstitution and storage	-20°C
Description of target	Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (PubMed:17418785).
Protein accession_num	NP_000624.2
Protein name	Apoptosis regulator Bcl-2
Clonality	Polyclonal
Purification	The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
Immunogen	The antiserum was produced against synthesized peptide derived from human BCL-2.
Dilution	The optimal working dilution should be determined by the end user.
Manufacturer - Specificity	BCL-2 (Ab-69) antibody detects endogenous levels of total BCL-2 protein.
Concentration	1 mg/ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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