Comparison

NFKBIA Antibody

Item no. OAAF01343
Manufacturer AVIVA Systems Biology
Amount 100 ug
Category
Type Antibody Polyclonal
Format Liquid
Applications WB, IF, IHC, ICC, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Citations Mattioli I, et al. (2004)J Immunol; 172(10): 6336-44.
Courtois G, et al. (2003)J Clin Invest; 112(7): 1108-15.
Nair A, et al. (2003) Oncogene; 22(1): 50-8.
Fan C, et al. (2002)J Cell Sci; 115(Pt 24): 4843-53.
Schubert SY, et al. (2002)FASE
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias EDAID2;IkappaBalpha;I-kappa-B-alpha;IKBA;ikB-alpha;MAD-3;major histocompatibility complex enhancer-binding protein MAD3;NF-kappa-B inhibitor alpha;NFKBI;nuclear factor of kappa light chain gene enhancer in B-cells;nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor,alpha.
Shipping Condition Cool pack
Available
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Applications
Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
Manufacturer - Category
Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature
Wet Ice
Molecular Weight
35 kDa
Manufacturer - Application Additional Information
WB: 1:500~1:3000; IHC: 1:50~1:100; ELISA: 1:10000
Gene symbol
NFKBIA
Gene Fullname
NFKB inhibitor alpha
Product format
Liquid
Reconstitution and storage
-20°C
Description of target
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
Protein accession_num
NP_065390.1
Protein name
NF-kappa-B inhibitor alpha
Clonality
Polyclonal
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
The antiserum was produced against synthesized peptide derived from human IkappaB-alpha.
Dilution
The optimal working dilution should be determined by the end user.
Manufacturer - Specificity
IκB-α (Ab-32/36) Antibody detects endogenous levels of total IκB-α protein.
Formulation
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
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