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MDM4 Antibody

MDM4 Antibody

Item no.	OAAF01643
Manufacturer	AVIVA Systems Biology
Amount	100 ug
Category	Oncology Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Adenocarcinoma Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies Astrocytoma By Organ Breast Cancer Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IF, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Citations	Shvarts A., Genomics 43:34-42(1997). Suzuki Y., Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases. Gregory S.G., Nature 441:315-321(2006)
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	BMFS6;Double minute 4 protein;double minute 4,human homolog of; p53-binding protein;HDMX;mdm2-like p53-binding protein;Mdm4 p53 binding protein homolog;MDM4 protein variant G;MDM4 protein variant Y;MDM4,p53 regulator;MDM4-related protein 1;MDMX;MRP1;p53-binding protein Mdm4;protein Mdm4;protein Mdmx.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	Enzyme-linked immunosorbent assay\|Immunofluorescence\|Immunohistochemistry\|Immunohistochemistry-Paraffin\|Western blot
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Research Areas/Cancer/Cancer Signal Transduction
Shipping Temperature	Wet Ice
Molecular Weight	54 kDa
Manufacturer - Application Additional Information	WB 1:500~1000 IHC 1:50~100 ELISA 1:40000
Gene symbol	MDM4
Gene Fullname	MDM4 regulator of p53
Product format	Liquid. PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Reconstitution and storage	-20°C
Description of target	Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions.
Protein accession_num	NP_001191100.1
Protein name	Protein Mdm4
Clonality	Polyclonal
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen	The antiserum was produced against synthesized peptide derived from human MDM4.
Dilution	The optimal working dilution should be determined by the end user.
Manufacturer - Specificity	MDM4 (Ab-367) antibody detects endogenous levels of total MDM4 protein.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 11/13/2025

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