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Anti-BCAR3 Antibody (Phospho-T130)

Anti-BCAR3 Antibody (Phospho-T130)

Item no.	OAAI00367
Manufacturer	AVIVA Systems Biology
Amount	100 ug
Category	Oncology Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Lymphoma Myeloma Melanoma Sarcoma Adenocarcinoma Flow Cytometry Immunohistochemistry Immunoprecipitation Western Blot ELISA Primary Antibodies Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, FC, IP, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Citations	Makkinje,A., et al. AND-34/BCAR3 regulates adhesion-dependent p130cas serine phosphorylation and breast cancer cell growth pattern. Cell. Signal. 21 (9), 1423-1435 (2009).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	AND-34;BCAR3,NSP family adaptor protein;breast cancer anti-estrogen resistance 3;breast cancer antiestrogen resistance 3 protein;breast cancer anti-estrogen resistance protein 3;dJ1033H22.2 (breast cancer anti-estrogen resistance 3);epididymis secretory sperm binding protein;mig-7;MIG7;migration inducting gene-7;novel SH2-containing protein 2;NSP2;SH2 domain-containing protein 3B;SH2D3B.
Similar products	NSP2, SH2D3B
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Polyclonal Antibodies/Phospho Specific, Root Catalog/Products/Primary Antibodies
Manufacturer - Isotype	Rabbit IgG
Shipping Temperature	Wet Ice
Molecular Weight	93
Manufacturer - Application Additional Information	WB: 0.1-1 ug/ml \| ELISA: 0.01-0.1 ug/ml \| IP: 2-5 ug/ml \| IHC: 2-10 ug/ml \| FC: Not tested
Gene symbol	BCAR3
Gene Fullname	BCAR3 adaptor protein, NSP family member
Product format	Liquid. This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer
Reconstitution and storage	The antibodies are stable for 24 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C-8C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
Description of target	Breast cancer anti-estrogen resistance 3 (BCAR3) is a also known as AND-34/BCAR3/NSP2 (BCAR3). Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. BCAR3 was identified in the search for genes involved in the development of estrogen resistance. The gene encodes a component of intracellular signal transduction that causes estrogen-independent prolifeRation in Human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	A synthetic peptide surrounding of RHIMDR-T*-PEKLK of human BCAR3 protein with a single phosphorylation site at Thr 130. This sequence is identical to human, rat, mouse, canis and bovine.
Manufacturer - Specificity	BCAE3
Concentration	100ug/200ul

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 11/13/2025

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