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Anti-Villin 2/Ezrin/p81 Polyclonal Antibody (OAAI00438)

Anti-Villin 2/Ezrin/p81 Polyclonal Antibody (OAAI00438)

Item no.	OAAI00438
Manufacturer	AVIVA Systems Biology
Amount	100 ug
Category	Oncology Neuroscience Neural Lineage Markers Antibodies By Cell Type Carcinoma Adenocarcinoma Immunohistochemistry Western Blot ELISA Primary Antibodies Microglia Markers
Type	Antibody Polyclonal
Applications	WB, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CVL, CVIL, VIL2, HEL-S-105
Similar products	VIL2, CVL, CVIL, HEL-S-105
Available
Gene symbol	EZR
Molecular weight	ca.81 kDa
Gene id	7430
Reconstitution and storage	The antibodies are stable for 12 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C to 8C for three month without detectable loss of activity. Avoid repeated freezing thawing cycles.
Description of target	Villin 2, also known as Ezrin, p81, 80K, or cytovillin, is a cytoplasmic peripheral membrane protein which is enriched in microvilli and other cell surface structures, Villin belongs to a member of the gelsolin family of calcium-regulated actin-binding proteins. Unlike the ubiquitously expressed gelsolin, villin expression is restricted to simple epithelia of the gastrointestinal and urogenital tracts. It is localized to the apical cytoplasm and brush borders of these cells. Villin functions in the regulation of actin dynamics in the apical epithelium, capping, nucleating and/or severing actin filaments in a calcium-dependent manner and regulating cell shape in response to external stimuli. Villin serves as a tyrosine kinase substRate, and is phosphorylated in EGF-stimulated cells. This protein plays a key role in cell surface structure adhesion, migRation and organization, and it has been implicated in various Human cancers.
Purification	The Rabbit IgG is purified by Epitope Affinity Purification.
Clonality	Polyclonal
Immunogen	A synthetic peptide corresponding to the C-term portion of Human Ezrin protein. This sequence is identical to Human, Rat, Mouse, dog, Monkey, zebra fish, and Human origins.
Drywet	Wet Ice

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 9/25/2025

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