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IL33 Antibody

IL33 Antibody

Item no.	OAED00263
Manufacturer	AVIVA Systems Biology
Amount	100 ug
Category	Neuroscience Neural Lineage Markers Neuroinflammation Molecular Targets for Neuroscience Neural Signaling Antibodies Cell Biology Cell Culture Cytokines Western Blot ELISA Primary Antibodies Immunostaining Neurodegeneration Markers Glial Cell Markers Neuronal Cell Markers
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Citations	Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimers disease: J. Chapuis, et al.; Mol. Psychiatry 14, 1004 (2009), Abstract; Nuclear Interleukin-33 Is Generally Expressed in Resting Endothelium but Rapidly Lost upon Angiogenic or Proinflammatory Activation: A.M. Kuchler, et al.; Am. J. Pathol. 173, 1229 (2008), Abstract; IL-33, the IL-1-like cytokine ligand for ST2 receptor, is a chromatin-associated nuclear factor in vivo : V. Carriere et al.; PNAS 104, 282 (2007), Abstract;
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	C9orf26;DVS27;DVS27-related protein;IL1F11;interleukin-1 family member 11;interleukin-33;NFEHEV;NF-HEV;nuclear factor for high endothelial venules;nuclear factor from high endothelial venules.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Manufacturer - Application Additional Information	ELISA Western Blot (1:1, 000)
Gene symbol	IL33
Gene Fullname	interleukin 33
Product format	Liquid. In PBS containing 0.02% sodium azide.
Reconstitution and storage	Long Term Storage : -20C Short Term Storage : +4C Handling : After opening, prepare aliquots and store at -20C. Avoid freeze/thaw cycles. Stable for at least 1 year after receipt when stored at -20C.
Description of target	Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells (PubMed:16286016). Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also involved in activation of mast cells, basophils, eosinophils and natural killer cells. Acts as a chemoattractant for Th2 cells, and may function as an "alarmin", that amplifies immune responses during tissue injury (PubMed:17853410, PubMed:18836528).
Nucleotide accession_num	NM_001199640.1; NM_001199641.1; NM_033439.3; XM_005251626.3; XM_005251627.1
Protein accession_num	NP_001186569.1; NP_001186570.1; NP_254274.1; XP_005251683.1; XP_005251684.1
Protein name	Interleukin-33
Clonality	Polyclonal
Purification	Protein A-affinity purified.
Immunogen	Recombinant human soluble IL-33 (interleukin-33) (aa 112-270)
Manufacturer - Specificity	Recognizes human, mouse and rat pro-IL-33 and mature IL-33.
Concentration	1mg/ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 11/27/2025

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