« Back
Home /
TOLLIP Antibody

TOLLIP Antibody

Item no.	OAPB00385
Manufacturer	AVIVA Systems Biology
Amount	0.1 mg
Category	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Metabolism Diabetes Antibodies By Cell Type Carcinoma Hematology Leukemia Lymphoma Obesity Western Blot ELISA Immunocytochemistry Primary Antibodies Immunostaining Neurodegeneration Markers Immunochemistry
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, ICC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Chicken (Gallus gallus domesticus), Cattle (Bovine)
Host	Rabbit
Conjugate/Tag	Unconjugated
Citations	Takeda K, Kaisho T, and Akira S. Toll-like receptors. Annu. Rev. Immunol.2003; 21:335-76.;Janeway CA Jr. and Medzhitov R. Innate immune recognition. Annu. Rev. Immunol.2002; 20:197-216.;McGettrick AF and Oâ€™Neill LAJ. The expanding family of MyD88-like adaptors in Toll-like receptor signal transduction. Mol. Imm.2004; 41:577-82.;Zhang G and Ghosh S. Negative regulation of Toll-like receptor-mediated signaling by Tollip. J. Biol. Chem.2002; 277:7059-65.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	adapter protein;IL-1RAcPIP;toll-interacting protein.
Similar products	TOLLIP
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Manufacturer - Application Additional Information	TOLLIP antibody can be used for the detection of TOLLIP by Western blot at 1 ug/ml. (Optimal dilution should be determined by user)
Gene symbol	TOLLIP
Gene Fullname	toll interacting protein
Product format	Liquid. TOLLIP Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution and storage	TOLLIP antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Description of target	Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity (PubMed:11751856). Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin-ATG8 family adapter and thus mediating autophagic clearance of ubiquitin conjugates. The TOLLIP-dependent selective autophagy pathway plays an important role in clearance of cytotoxic polyQ proteins aggregates (PubMed:25042851).
Nucleotide accession_num	NM_019009.3
Protein accession_num	https://www.ncbi.nlm.nih.gov/protein/AAH18272
Protein name	Toll interacting protein [Homo sapiens]\|Toll-interacting protein
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	TOLLIP antibody was raised against a 16 amino acid synthetic peptide from near the center of human TOLLIP. The immunogen is located within amino acids 70 - 120 of TOLLIP.
Homology	Human; Mouse; Rat
Concentration	1 mg/ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

OAPB00385-datasheet.pdf

Request safety datasheet

Simple Order Order Subscription

Amount: 0.1 mg

available

Delivery expected until 2/12/2026

Express Delivery: Save 8 days

Compare

Add to wishlist

Get an offer