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TWEAK Antibody

TWEAK Antibody

Item no.	OAPB00405
Manufacturer	AVIVA Systems Biology
Amount	0.1 mg
Category	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Antibodies By Cell Type Cell Biology Cell Movement Cell Adhesion Obesity Cell Status Necrosis Apoptosis Immunohistochemistry Western Blot ELISA Immunofluorescence Cell Stainings ECM Cardiovascular Research Ischemia & Reperfusion Injury Primary Antibodies Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IF, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Conjugate/Tag	Unconjugated
Citations	TWEAK antibody can be stored at 4C, stable for one year. Wiley SR and Winkles JA. TWEAK, a member of the TNF superfamily, is a multifunctional cytokine that binds the TweakR/Fn14 receptor. Cyto. And Growth Factor Rev. 2003; 14:241-9.;Chicheportiche Y, Bourdon PR, Xu H, et al. TWEAK, a new secreted ligand in the tumor necrosis factor family that weakly induces apoptosis. J. Biol. Chem. 1997; 272:32401-10.; Lynch CN, Wang YC, Lund JK, et al. TWEAK induces angiogenesis and proliferation of endothelial cells. J. Biol. Chem. 1999; 274:8455-9.;Chicheportiche Y, Chicheportiche R, Sizing I, et al. Proinflammatory activity of TWEAK on human dermal fibroblasts and synoviocytes: blocking and enhancing effects of anti-TWEAK monoclonal antibodies. Arthr. Res. 2002; 4:126-33. 5. Kaplan MJ, Lewis EE, Shelden EA, et al. The apoptotic ligands TRAIL, TWEAK, and Fas ligand mediate monocyte death induced by autologous lupus T cells. J. Immunol. 2002; 169:6020-9.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	APO3 ligand;APO3/DR3 ligand;APO3L;DR3LG;TNF-related WEAK inducer of apoptosis;TNFSF12-TNFSF13 protein;TNLG4A;tumor necrosis factor (ligand) superfamily,member 12;tumor necrosis factor (ligand) superfamily,member 12-member 13;tumor necrosis factor ligand 4A;tumor necrosis factor ligand superfamily member 12;tumor necrosis factor superfamily member 12;TWEAK;TWE-PRIL.
Similar products	TWEAK
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	Enzyme-linked immunosorbent assay\|Immunofluorescence\|Immunohistochemistry-Paraffin\|Western blot
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	Predicted: 27 and 36 kD Observed: 27 and 36 kD
Manufacturer - Application Additional Information	TWEAK antibody can be used for the detection of TWEAK by Western blot at 0.5 - 1 ug/ml. (Optimal dilution should be determined by user)
Gene symbol	TNFSF12\|TNFSF12-TNFSF13
Gene Fullname	TNF superfamily member 12\|TNFSF12-TNFSF13 readthrough
Product format	Liquid. TWEAK Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution and storage	TWEAK antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Description of target	Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion.
Protein accession_num	https://www.ncbi.nlm.nih.gov/protein/NP_003800
Protein name	Tumor necrosis factor ligand superfamily member 12\|tumor necrosis factor ligand superfamily member 12 proprotein [Homo sapiens]
Clonality	Polyclonal
Purification	Protein A Purified
Immunogen	Anti-TWEAK antibody (3791) was raised against recombinant human TWEAK protein.
Homology	Human; Mouse; Rat
Concentration	1 mg/ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg

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Delivery expected until 12/25/2025

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